17. Glutamic Acid

  1. Virendra S. Bisaria and
  2. Akihiko Kondo
  1. Takashi Hirasawa1 and
  2. Hiroshi Shimizu2

Published Online: 4 APR 2014

DOI: 10.1002/9781118845394.ch17

Bioprocessing of Renewable Resources to Commodity Bioproducts

Bioprocessing of Renewable Resources to Commodity Bioproducts

How to Cite

Hirasawa, T. and Shimizu, H. (2014) Glutamic Acid, in Bioprocessing of Renewable Resources to Commodity Bioproducts (eds V. S. Bisaria and A. Kondo), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9781118845394.ch17

Author Information

  1. 1

    Department of Bioengineering, Tokyo Institute of Technology

  2. 2

    Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University

Publication History

  1. Published Online: 4 APR 2014
  2. Published Print: 7 APR 2014

ISBN Information

Print ISBN: 9781118175835

Online ISBN: 9781118845394

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Keywords:

  • glutamic acid;
  • Corynebacterium glutamicum;
  • metabolic engineering;
  • γ-aminobutyric acid;
  • poly(γ-glutamic acid);
  • 5-aminolevulinic acid

Summary

The acidic amino acid glutamic acid is considered as one of the most important building blocks for chemical synthesis. Glutamic acid is currently produced from inexpensive sugars via the glutamic-acid-producing microorganism Corynebacterium glutamicum. The molecular mechanism and metabolic engineering of glutamic acid production via C. glutamicum have been reported. Moreover, other chemicals from glutamic acid such as γ-aminobutyric acid, poly(γ-glutamic acid), and 5-aminolevulinic acid have also been produced by microorganisms. This chapter reviews the molecular mechanism and metabolic engineering of glutamic acid production by C. glutamicum and the production of chemicals from glutamic acid by various microorganisms. The potential use of glutamic acid as a building block for producing chemicals is also briefly discussed.