10. Brain Imaging

  1. Joseph Zohar4,5
  1. David R. Rosenberg1,2,
  2. Phillip C. Easter3 and
  3. Georgia Michalopoulou1,2

Published Online: 12 JUN 2012

DOI: 10.1002/9781119941125.ch10

Obsessive-Compulsive Disorder: Current Science and Clinical Practice

Obsessive-Compulsive Disorder: Current Science and Clinical Practice

How to Cite

Rosenberg, D. R., Easter, P. C. and Michalopoulou, G. (2012) Brain Imaging, in Obsessive-Compulsive Disorder: Current Science and Clinical Practice (ed J. Zohar), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119941125.ch10

Editor Information

  1. 4

    Psychiatry Department A, Division of Psychiatry, Chaim Sheba Medical Center, Tel Hashomer, Israel

  2. 5

    Tel Aviv University, Tel Aviv, Israel

Author Information

  1. 1

    Children's Hospital of Michigan, USA

  2. 2

    Wayne State University School of Medicine, Department of Psychiatry, University Health Center, Detroit, MI, USA

  3. 3

    Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, University Health Center, Detroit, MI, USA

Publication History

  1. Published Online: 12 JUN 2012
  2. Published Print: 13 MAR 2012

ISBN Information

Print ISBN: 9780470711255

Online ISBN: 9781119941125

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Keywords:

  • brain imaging, neurobiological underpinnings of OCD;
  • adult and pediatric OCD, cortico-striatal-thalamic alterations;
  • OCD, and functional neurochemical assessment;
  • MRS, direct and brain chemistry in vivo measurement;
  • amygdala abnormalities in paediatric OCD, prefrontal cortex;
  • supramarginal gyrus in adult OCD, problems in set shifting;
  • NAA, a putative neuronal marker in OCD pathogenesis;
  • glutamate abnormalities in OCD pathogenesis;
  • memantine augmentation, effectiveness in paediatric, adult OCD

Summary

This chapter contains sections titled:

  • Neuroimaging modalities

  • Structural assessment of OCD

  • Functional neuroimaging studies of OCD

  • Neurochemistry

  • Conclusion

  • Acknowledgements

  • References