11. The Genetics of Obsessive-Compulsive Disorder: Current Status

  1. Joseph Zohar2,3
  1. David L. Pauls

Published Online: 12 JUN 2012

DOI: 10.1002/9781119941125.ch11

Obsessive-Compulsive Disorder: Current Science and Clinical Practice

Obsessive-Compulsive Disorder: Current Science and Clinical Practice

How to Cite

Pauls, D. L. (2012) The Genetics of Obsessive-Compulsive Disorder: Current Status, in Obsessive-Compulsive Disorder: Current Science and Clinical Practice (ed J. Zohar), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119941125.ch11

Editor Information

  1. 2

    Psychiatry Department A, Division of Psychiatry, Chaim Sheba Medical Center, Tel Hashomer, Israel

  2. 3

    Tel Aviv University, Tel Aviv, Israel

Author Information

  1. Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Publication History

  1. Published Online: 12 JUN 2012
  2. Published Print: 13 MAR 2012

ISBN Information

Print ISBN: 9780470711255

Online ISBN: 9781119941125

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Keywords:

  • genetics of OCD, the current status;
  • Twin studies and genetic factors in complex disorder manifestation;
  • genetic relationship between OCD, tic and anxiety;
  • genetic factors, role in OCD aetiology;
  • environmental/cultural factors in increased risk of OCD;
  • Grabe and colleagues' findings, familial disorder in first-degree relatives and OCD;
  • complex segregation analyses and underlying genetic model;
  • OCD, GWAS or whole-genome, of risk genes of relatively small effect;
  • IOCDFGC and genome-wide association studies of OCD

Summary

This chapter contains sections titled:

  • Introduction

  • Twin studies

  • Family studies

  • Segregation analyses

  • Candidate gene studies

  • Genetic linkage studies

  • Future work

  • Acknowledgements

  • References