9. Serotonin and Beyond: A Neurotransmitter Perspective of OCD

  1. Joseph Zohar1,2
  1. Anat Abudy1,
  2. Alzbeta Juven-Wetzler1,
  3. Rachel Sonnino1 and
  4. Joseph Zohar1,2

Published Online: 12 JUN 2012

DOI: 10.1002/9781119941125.ch9

Obsessive-Compulsive Disorder: Current Science and Clinical Practice

Obsessive-Compulsive Disorder: Current Science and Clinical Practice

How to Cite

Abudy, A., Juven-Wetzler, A., Sonnino, R. and Zohar, J. (2012) Serotonin and Beyond: A Neurotransmitter Perspective of OCD, in Obsessive-Compulsive Disorder: Current Science and Clinical Practice (ed J. Zohar), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119941125.ch9

Editor Information

  1. 1

    Psychiatry Department A, Division of Psychiatry, Chaim Sheba Medical Center, Tel Hashomer, Israel

  2. 2

    Tel Aviv University, Tel Aviv, Israel

Author Information

  1. 1

    Psychiatry Department A, Division of Psychiatry, Chaim Sheba Medical Center, Tel Hashomer, Israel

  2. 2

    Tel Aviv University, Tel Aviv, Israel

Publication History

  1. Published Online: 12 JUN 2012
  2. Published Print: 13 MAR 2012

ISBN Information

Print ISBN: 9780470711255

Online ISBN: 9781119941125

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Keywords:

  • serotonin and beyond, neurotransmitter perspective of OCD;
  • neurotransmitters, a pharmacological challenge in OCD;
  • radioligands for neuroimaging techniques;
  • serotonin on OCD, CSF metabolite levels in brain;
  • blood–CSF barrier to amino acids, and serotonin and metabolites;
  • 5-HT in biopathology of OCD;
  • pharmacological, abnormal serotonin function in OCD;
  • dopamine in OCD conflicting, OC and dopamine neurotransmission;
  • serotonin–dopamine and SSRI effect on dopamine release;
  • two neurotransmitter relationship and SSRI effect in OCD treatment

Summary

This chapter contains sections titled:

  • Serotonin

  • Dopamine

  • Glutamate

  • Serotonin: is it the one to blame?

  • The puzzle of antipsychotics and OCD: Is dopamine the answer?

  • So, is it a question of location? (Or … location, location, location?)

  • References