10. Protection Against Abuse and Research Involving Vulnerable Populations

  1. Felicity Callard1,
  2. Norman Sartorius2,
  3. Julio Arboleda-Flórez3,
  4. Peter Bartlett4,
  5. Hanfried Helmchen5,
  6. Heather Stuart3,
  7. Jose Taborda6 and
  8. Graham Thornicroft1

Published Online: 17 APR 2012

DOI: 10.1002/9781119945352.ch10

Mental Illness, Discrimination and the Law: Fighting for Social Justice

Mental Illness, Discrimination and the Law: Fighting for Social Justice

How to Cite

Callard, F., Sartorius, N., Arboleda-Flórez, J., Bartlett, P., Helmchen, H., Stuart, H., Taborda, J. and Thornicroft, G. (2012) Protection Against Abuse and Research Involving Vulnerable Populations, in Mental Illness, Discrimination and the Law: Fighting for Social Justice, John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119945352.ch10

Author Information

  1. 1

    Health Service and Population Research Department, Institute of Psychiatry, King's College London, UK

  2. 2

    Association for the Improvement of Mental Health Programmes, Geneva, Switzerland

  3. 3

    Queen's University, Kingston, Ontario, Canada

  4. 4

    School of Law and Institute of Mental Health, University of Nottingham, UK

  5. 5

    Charité – University Medicine Berlin, Germany

  6. 6

    Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil

Publication History

  1. Published Online: 17 APR 2012
  2. Published Print: 13 APR 2012

ISBN Information

Print ISBN: 9781119953548

Online ISBN: 9781119945352

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Keywords:

  • human dignity;
  • ethical obligations;
  • ethics of human research;
  • medical research;
  • Nuremberg Code;
  • protection against abuse;
  • research ethics;
  • vulnerable research participants

Summary

We consider the historical basis and the current ethical framework for the conduct of medical research. The roots of the present system of medical ethics committees/institutional review boards can be traced to the Nuremberg Code, which set out the lessons learned from the Nuremberg Trials related to Nazi atrocities in World War 2. The 10 elements of this Code have had a profound and enduring effect on all subsequent ethical regulations, including, for example, the Declaration of Helsinki. We go on to discuss the concepts of capacity, competence and vulnerability, and their various applications in illustrative country examples. A series of relevant legal responses and remedies are summarised.