19. Nonreactive and Purely Reactive Doses in Observational Studies

  1. Carlo Berzuini,
  2. Philip Dawid and
  3. Luisa Bernardinelli
  1. Paul R. Rosenbaum

Published Online: 25 JUN 2012

DOI: 10.1002/9781119945710.ch19

Causality: Statistical Perspectives and Applications

Causality: Statistical Perspectives and Applications

How to Cite

Rosenbaum, P. R. (2012) Nonreactive and Purely Reactive Doses in Observational Studies, in Causality: Statistical Perspectives and Applications (eds C. Berzuini, P. Dawid and L. Bernardinelli), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119945710.ch19

Editor Information

  1. Statistical Laboratory, Centre for Mathematical Sciences, University of Cambridge, Cambridge, UK

Author Information

  1. Wharton School, University of Pennsylvania, Philadelphia, Pennsylvania, USA

Publication History

  1. Published Online: 25 JUN 2012
  2. Published Print: 13 JUL 2012

Book Series:

  1. Wiley Series in Probability and Statistics

Book Series Editors:

  1. Walter A. Shewhart and
  2. Samuel S. Wilks

ISBN Information

Print ISBN: 9780470665565

Online ISBN: 9781119945710

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Keywords:

  • nonreactive and purely reactive doses, in observational studies;
  • dose–response relationship;
  • chemotherapy in ovarian cancer, its effectiveness or its toxicness;
  • MO–GO difference, weeks with chemotherapy;
  • covariates, outcomes, and treatment assignment in matched pairs;
  • reactive, nonreactive doses of treatment;
  • nonreactive dose in treatment, purely reactive dose in the experimental;
  • Wilcoxon's signed rank statistic, dose usage ways;
  • MO and GO groups, sensitivity of toxicity difference and bias;
  • design sensitivity, with purely reactive doses

Summary

This chapter contains sections titled:

  • Introduction: Background, example

  • Various concepts of dose

  • Design sensitivity

  • Summary

  • References