10. Lipids: Cellular Metabolism

  1. John W. Erdman Jr. PhD3,
  2. Ian A. Macdonald PhD4 and
  3. Steven H. Zeisel MD, PhD5
  1. Peter J. H. Jones PhD1 and
  2. Andrea A. Papamandjaris2

Published Online: 18 JUN 2012

DOI: 10.1002/9781119946045.ch10

Present Knowledge in Nutrition, Tenth Edition

Present Knowledge in Nutrition, Tenth Edition

How to Cite

Jones, P. J. H. and Papamandjaris, A. A. (2012) Lipids: Cellular Metabolism, in Present Knowledge in Nutrition, Tenth Edition (eds J. W. Erdman, I. A. Macdonald and S. H. Zeisel), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119946045.ch10

Editor Information

  1. 3

    Urbana, Illinois, USA

  2. 4

    Nottingham, England

  3. 5

    UNC Nutrition Research Institute, Department of Nutrition, University of North Carolina at Chapel Hill, 500 Laureate Way, Rm 2218, Kannapolis, NC 28081, USA

Author Information

  1. 1

    Richardson Centre for Functional Foods, University of Manitoba, Smartpark Research and Technology Park, 196 Innovation Drive, Winnipeg, Manitoba R3T 6C5, Canada

  2. 2

    NestléInc., Medical and Scientific Unit, North York, Ontario M2N 6S8, Canada

Publication History

  1. Published Online: 18 JUN 2012
  2. Published Print: 20 JUL 2012

ISBN Information

Print ISBN: 9780470959176

Online ISBN: 9781119946045



  • lipids, and cellular metabolism;
  • functional foods and fatty acids, as added health benefits;
  • dietary lipid selection, for preventing development of chronic diseases;
  • fatty acids, position of first double bond from acyl chain methyl end;
  • essential fatty acids in humans, and its dietary importance;
  • polyunsaturated fatty acids in gene expression in lipid/energy metabolism;
  • polyunsaturated fatty acids, eicosanoids in dietary fatty acid composition;
  • lipid biosynthesis, indicators for fatty acid deficiency, triene-to-tetraene ratio;
  • cholesterol biosynthesis, of more than 20 steps;
  • qualitative fat consumption, and diet fatty acid metabolic action


This chapter contains sections titled:

  • Introduction

  • Summary

  • Dietary Sources of Lipids

  • Lipid Biosynthesis

  • Cellular Roles of Lipids

  • Eicosanoid Production and Regulation

  • Dietary Requirements for Fatty Acids

  • Dietary Fatty Acids and Disease Risk

  • Future Directions

  • Acknowledgments