14. Portal Hypertension: Nonsurgical and Surgical Management
- Eugene R. Schiff MD, MACP, FRCP3,
- Willis C. Maddrey MD, MACP, FRCP4,
- Michael F. Sorrell MD, FACP5
Published Online: 31 OCT 2011
DOI: 10.1002/9781119950509.ch14
Copyright © 2012 John Wiley & Sons Ltd.
Book Title
Schiff's Diseases of the Liver, Eleventh Edition
Additional Information
How to Cite
Maruyama, H. and Sanyal, A. J. (2011) Portal Hypertension: Nonsurgical and Surgical Management, in Schiff's Diseases of the Liver, Eleventh Edition (eds E. R. Schiff, W. C. Maddrey and M. F. Sorrell), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119950509.ch14
Editor Information
- 3
Center for Liver Diseases and Schiff Liver Institute, University of Miami Miller School of Medicine, Miami, FL, USA
- 4
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA
- 5
University of Nebraska College of Medicine, Omaha, NE, USA
Publication History
- Published Online: 31 OCT 2011
- Published Print: 9 DEC 2011
ISBN Information
Print ISBN: 9780470654682
Online ISBN: 9781119950509
- Summary
- Chapter
- References
Keywords:
- Portal hypertension;
- nonsurgical management;
- surgical management;
- liver;
- cirrhosis;
- gastroesophageal varices;
- gastrointestinal bleeding;
- portal hypertensive gastropathy;
- pharmacological treatment;
- endoscopy;
- intervention
Summary
Portal hypertension is defined as an increase in the pressure gradient between the portal vein and the inferior vena cava of over 5 mmHg. It causes bleeding from gastroesophageal varices and/or portal hypertensive gastropathy, ascites, and hepatic encephalopathy. These symptoms are the principal complications of cirrhosis, and affect the prognosis of the patients. The control of portal hypertension and the treatment of its complications are the cornerstones of management of cirrhosis. The optimal management of portal hypertension requires a clear understanding of its anatomic and physiological basis, natural history, and utility of specific therapies at specific stages in the clinical course of portal hypertension. This chapter provides a guide to nonsurgical and surgical management of portal hypertension.