2. Laboratory Tests

  1. Eugene R. Schiff MD, MACP, FRCP3,
  2. Willis C. Maddrey MD, MACP, FRCP4 and
  3. Michael F. Sorrell MD, FACP5
  1. H. Franklin Herlong MD1 and
  2. Mack C. Mitchell Jr MD2

Published Online: 31 OCT 2011

DOI: 10.1002/9781119950509.ch2

Schiff's Diseases of the Liver, Eleventh Edition

Schiff's Diseases of the Liver, Eleventh Edition

How to Cite

Herlong, H. F. and Mitchell, M. C. (2011) Laboratory Tests, in Schiff's Diseases of the Liver, Eleventh Edition (eds E. R. Schiff, W. C. Maddrey and M. F. Sorrell), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119950509.ch2

Editor Information

  1. 3

    Center for Liver Diseases and Schiff Liver Institute, University of Miami Miller School of Medicine, Miami, FL, USA

  2. 4

    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA

  3. 5

    University of Nebraska College of Medicine, Omaha, NE, USA

Author Information

  1. 1

    Department of Gastroenterology, Johns Hopkins Bayview Medical School, Baltimore, MD, USA

  2. 2

    Johns Hopkins Bayview Medical Center, Baltimore, MD, USA

Publication History

  1. Published Online: 31 OCT 2011
  2. Published Print: 9 DEC 2011

ISBN Information

Print ISBN: 9780470654682

Online ISBN: 9781119950509



  • laboratory tests;
  • drug-induced liver injury (DILI);
  • serum enzyme tests;
  • serum aminotransferases;
  • AST and ALT, liver cells;
  • hepatitis C, ALT, AST levels;
  • isocitrate dehydrogenase (ICDH);
  • bilirubin metabolism;
  • hepatic dysfunction;
  • liver biopsy


This chapter contains sections titled:

  • Tests for detection of injury to hepatocytes (serum enzyme tests)

  • Tests of the liver's biosynthetic capacity

  • Tests of the liver's capacity to transport organic anions and to metabolize organic compounds

  • Tests used to detect fibrosis in the liver

  • Tests used to detect chronic inflammation or fibrosis in the liver or altered immunoregulation

  • Use of liver function tests

  • Further reading

  • References