48. The Role of Retransplantation

  1. Eugene R. Schiff MD, MACP, FRCP3,
  2. Willis C. Maddrey MD, MACP, FRCP4 and
  3. Michael F. Sorrell MD, FACP5
  1. Peter L. Abt MD1 and
  2. Kim M. Olthoff MD2

Published Online: 31 OCT 2011

DOI: 10.1002/9781119950509.ch48

Schiff's Diseases of the Liver, Eleventh Edition

Schiff's Diseases of the Liver, Eleventh Edition

How to Cite

Abt, P. L. and Olthoff, K. M. (2011) The Role of Retransplantation, in Schiff's Diseases of the Liver, Eleventh Edition (eds E. R. Schiff, W. C. Maddrey and M. F. Sorrell), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119950509.ch48

Editor Information

  1. 3

    Center for Liver Diseases and Schiff Liver Institute, University of Miami Miller School of Medicine, Miami, FL, USA

  2. 4

    Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA

  3. 5

    University of Nebraska College of Medicine, Omaha, NE, USA

Author Information

  1. 1

    Department of Surgery, Division of Transplant Surgery, The Hospital of the University of Pennsylvania, Philadelphia, PA, USA

  2. 2

    Donald Guthrie Professor of Surgery, The Hospital of the University of Pennsylvania, Philadelphia, PA, USA

Publication History

  1. Published Online: 31 OCT 2011
  2. Published Print: 9 DEC 2011

ISBN Information

Print ISBN: 9780470654682

Online ISBN: 9781119950509

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Keywords:

  • Liver transplant;
  • retransplantation;
  • hepatitis C;
  • model for end-stage liver disease;
  • donor risk index

Summary

Survival after retransplantation of the liver is inferior to the outcome with primary liver transplantation. The timing of retransplantation relative to the initial transplant, health of the recipient, quality of the donor, and primary hepatic disease are important components in the decision to proceed with retransplantion and to avoid futility as well as to maximize utility. Despite continued improvement with retransplantation, the appropriateness of retransplantation has been questioned due to ethical and economic grounds.