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HugZ from Helicobacter pylori

  1. Yonglin Hu,
  2. Da-Cheng Wang

Published Online: 15 SEP 2012

DOI: 10.1002/9781119951438.eibc2057

Encyclopedia of Inorganic and Bioinorganic Chemistry

Encyclopedia of Inorganic and Bioinorganic Chemistry

How to Cite

Hu, Y. and Wang, D.-C. 2012. HugZ from Helicobacter pylori. Encyclopedia of Inorganic and Bioinorganic Chemistry. .

Author Information

  1. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, PR, China

Publication History

  1. Published Online: 15 SEP 2012

Abstract

HugZ is a heme oxygenase (HO) from Helicobacter pylori. It adopts a split-barrel fold, distinct from that of canonical HOs such as human HO-1. It belongs to a new hemoprotein family that has members from various pathogenic bacteria. This review discusses the structural features of HugZ and its interactions with heme.

3D Structure

Keywords:

  • heme oxygenase;
  • iron acquisition;
  • pathogenic bacteria;
  • Helicobacter pylori