Dark-Operative Protochlorophyllide Oxidoreductase
Published Online: 15 SEP 2012
Copyright © 2011 John Wiley & Sons, Ltd. All rights reserved.
Encyclopedia of Inorganic and Bioinorganic Chemistry
How to Cite
Moser, J. and Schubert, W.-D. 2012. Dark-Operative Protochlorophyllide Oxidoreductase. Encyclopedia of Inorganic and Bioinorganic Chemistry. .
- Published Online: 15 SEP 2012
Dark-operative (or light-independent) protochlorophyllide oxidoreductase is an enzyme of the chlorophyll and bacteriochlorophyll biosynthetic pathway catalyzing the reduction of protochlorophyllide to chlorophyllide. DPOR catalysis involves the ATP-dependent, two-electron reduction and trans-hydrogenation of the C17–C18 double bond of the conjugated D ring system of protochlorophyllide converting the pheoporphyrin backbone of protochlorophyllide to a chlorin macrocycle characteristic of all chlorophylls. The process is mediated by the dynamic interaction of two DPOR subcomplexes, each carrying redox active 4Fe–4S clusters. We discuss all available structural and biochemical data on this enzyme and compare it to nitrogenase and other related enzyme systems.
- chlorophyll biosynthesis;
- bacteriochlorophyll biosynthesis;
- ATP-dependent electron transfer