2. Evaluating New Diagnostic Tests

  1. Matthew Thompson1,2 and
  2. Ann Van den Bruel2

Published Online: 1 NOV 2011

DOI: 10.1002/9781119951827.ch2

Diagnostic Tests Toolkit

Diagnostic Tests Toolkit

How to Cite

Thompson, M. and Van den Bruel, A. (2011) Evaluating New Diagnostic Tests, in Diagnostic Tests Toolkit, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119951827.ch2

Author Information

  1. 1

    Department of Family Medicine, Oregon Health & Science University, Portland, Oregon, USA

  2. 2

    Department of Primary Care Health Sciences, University of Oxford, Oxford, UK

Publication History

  1. Published Online: 1 NOV 2011
  2. Published Print: 7 OCT 2011

Book Series:

Book Series Editors:

  1. Carl Heneghan,
  2. Rafael Perera and
  3. Douglas Badenoch

ISBN Information

Print ISBN: 9780470657584

Online ISBN: 9781119951827



  • new diagnostic test evaluation;
  • new tests, developed;
  • health technology assessment (HTA);
  • diagnostic tests;
  • diagnosing illness, target;
  • test, technically sound;
  • role of new tests;
  • ability of a test;
  • nested case–control study;
  • effect of test


This chapter contains sections titled:

  • Technical accuracy (‘Can it work?’)

  • Place in the clinical pathway (‘Where does the test fit in the existing clinical pathway?’)

  • Ability of the test to diagnose or exclude the target condition (‘Does it work in patients?’)

  • The effect of the test on patient outcomes (‘Are patients better off?’)

  • Cost-effectiveness (‘Is it worth the cost?’)

  • Further reading