8. Using Diagnostic Information in Clinical Practice

  1. Matthew Thompson1,2 and
  2. Ann Van den Bruel2

Published Online: 1 NOV 2011

DOI: 10.1002/9781119951827.ch8

Diagnostic Tests Toolkit

Diagnostic Tests Toolkit

How to Cite

Thompson, M. and Van den Bruel, A. (2011) Using Diagnostic Information in Clinical Practice, in Diagnostic Tests Toolkit, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119951827.ch8

Author Information

  1. 1

    Department of Family Medicine, Oregon Health & Science University, Portland, Oregon, USA

  2. 2

    Department of Primary Care Health Sciences, University of Oxford, Oxford, UK

Publication History

  1. Published Online: 1 NOV 2011
  2. Published Print: 7 OCT 2011

Book Series:

Book Series Editors:

  1. Carl Heneghan,
  2. Rafael Perera and
  3. Douglas Badenoch

ISBN Information

Print ISBN: 9780470657584

Online ISBN: 9781119951827



  • diagnostic information;
  • evidence-based diagnosis;
  • single 2 × 2 table;
  • data validity;
  • over- and under-diagnosis;
  • clinical diagnostic problems;
  • stages and strategies;
  • action versus testing thresholds;
  • multivariable analyses;
  • prediction rule


This chapter contains sections titled:

  • Validity of data

  • Problem-solving strategies that clinicians use in diagnosis

  • Action thresholds versus testing thresholds (‘Will the test change my management?’)

  • Methods for combining test results

  • Multivariable analyses

  • How are clinical prediction rules developed?

  • How to select a prediction rule for clinical practice

  • Further reading