15. Chronic Liver Disease

  1. Shanthi V. Sitaraman MD, PhD2 and
  2. Lawrence S. Friedman MD3,4,5,6
  1. Preeti A. Reshamwala MD

Published Online: 4 JAN 2012

DOI: 10.1002/9781119959762.ch15

Essentials of Gastroenterology

Essentials of Gastroenterology

How to Cite

Reshamwala, P. A. (2012) Chronic Liver Disease, in Essentials of Gastroenterology (eds S. V. Sitaraman and L. S. Friedman), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119959762.ch15

Editor Information

  1. 2

    Division of Digestive Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA

  2. 3

    Harvard Medical School, Boston, MA, USA

  3. 4

    Tufts University School of Medicine, Boston, MA, USA

  4. 5

    Department of Medicine, Newton-Wellesley Hospital, Newton, MA, USA

  5. 6

    Massachusetts General Hospital, Boston, MA, USA

Author Information

  1. Southern California Liver Centers, Coronado, CA, USA

Publication History

  1. Published Online: 4 JAN 2012
  2. Published Print: 17 FEB 2012

ISBN Information

Print ISBN: 9780470656259

Online ISBN: 9781119959762



  • chronic liver disease;
  • liver parenchyma, progressive destruction, regeneration;
  • cirrhosis, fatal consequence of untreated chronic liver disease;
  • compensated cirrhosis, and anorexia, weight loss, weakness;
  • complete blood count and metabolic panel obtained;
  • causes of chronic liver disease;
  • AIH, chronic inflammatory condition of liver;
  • PBC, autoimmune disorder;
  • vascular disorders of liver, PVT, BCS;
  • HH, Wilson disease (WD), A1ATD


This chapter contains sections titled:

  • General

  • Clinical Features

  • Diagnosis

  • Autoimmune Hepatitis

  • Primary Biliary Cirrhosis (PBC)

  • Primary Sclerosing Cholangitis

  • Hemochromatosis

  • Wilson disease (WD)

  • Alpha-1 Antitrypsin Deficiency (A1ATD)

  • Vascular Disorders of the Liver

  • Further Reading