43. Preterm Premature Rupture of Membranes
- John T. Queenan MD3,
- Catherine Y. Spong MD4,
- Charles J. Lockwood MD5
Published Online: 4 JAN 2012
DOI: 10.1002/9781119963783.ch43
Copyright © 2012 John Wiley and Sons, Ltd
Book Title

Queenan's Management of High-Risk Pregnancy: An Evidence-Based Approach, Sixth Edition
Additional Information
How to Cite
Mercer, B. M. (2012) Preterm Premature Rupture of Membranes, in Queenan's Management of High-Risk Pregnancy: An Evidence-Based Approach, Sixth Edition (eds J. T. Queenan, C. Y. Spong and C. J. Lockwood), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119963783.ch43
Editor Information
- 3
Department of Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, DC, USA
- 4
Bethesda, MD, USA
- 5
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA
Publication History
- Published Online: 4 JAN 2012
- Published Print: 24 FEB 2012
ISBN Information
Print ISBN: 9780470655764
Online ISBN: 9781119963783
- Summary
- Chapter
- References
Keywords:
- preterm premature rupture of membranes (PROM);
- rupture of fetal membranes, before labor;
- spontaneous membrane rupture, weakening of membranes;
- women suffering PPROM, recurrence in future pregnancies;
- membrane rupture diagnosis, sterile speculum examination;
- cervical cultures;
- delivery after PPROM, in clinical chorioamnionitis;
- management of woman with PROM;
- cerclage, risk factor for PROM;
- cessation of leakage with membrane resealing
Summary
Rupture of fetal membranes before the onset of labor (premature rupture of membranes) complicates 8–10% of pregnancies, and is responsible for nearly one-third of preterm births. Premature rupture of membranes, especially preterm premature rupture of membranes, has been associated with brief latency from membrane rupture to delivery, an increased risk of chorio-amnionitis, and umbilical cord compression. As such, preterm premature rupture of membranes is associated with increased risk of perinatal complications. An understanding of gestational age-dependent risks of delivery, the risks and potential benefits of conservative management, and opportunities to reduce complications of preterm birth will help clinicians improve outcomes after this common pregnancy complication.
