55. Genetic Amniocentesis and Chorionic Villus Sampling

  1. John T. Queenan MD2,
  2. Catherine Y. Spong MD3 and
  3. Charles J. Lockwood MD4
  1. Ronald J. Wapner MD

Published Online: 4 JAN 2012

DOI: 10.1002/9781119963783.ch55

Queenan's Management of High-Risk Pregnancy: An Evidence-Based Approach, Sixth Edition

Queenan's Management of High-Risk Pregnancy: An Evidence-Based Approach, Sixth Edition

How to Cite

Wapner, R. J. (2012) Genetic Amniocentesis and Chorionic Villus Sampling, in Queenan's Management of High-Risk Pregnancy: An Evidence-Based Approach, Sixth Edition (eds J. T. Queenan, C. Y. Spong and C. J. Lockwood), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119963783.ch55

Editor Information

  1. 2

    Department of Obstetrics and Gynecology, Georgetown University School of Medicine, Washington, DC, USA

  2. 3

    Bethesda, MD, USA

  3. 4

    Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA

Author Information

  1. Department of Obstetrics and Gynecology, Columbia University Medical Center, New York, NY, USA

Publication History

  1. Published Online: 4 JAN 2012
  2. Published Print: 24 FEB 2012

ISBN Information

Print ISBN: 9780470655764

Online ISBN: 9781119963783

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Keywords:

  • procedures;
  • genetic amniocentesis and CVS;
  • chorionic villus sampling (CVS);
  • prenatal diagnosis, cytogenetic indications;
  • amniocentesis;
  • ultrasound imaging, optimal needle insertion path;
  • multiple gestations and amniocentesis;
  • CVS, and transabdominal CVS;
  • pregnancy loss after CVS;
  • array comparative genomic hybridization, in prenatal diagnosis

Summary

The prenatal diagnosis of genetic disorders is an important component of modern obstetrics. The most common techniques used for obtaining fetal tissues for genetic testing are amniocentesis and chorionic villus sampling. In this chapter we review the most frequent indications for amniocentesis and chorionic villus sampling, and consider the techniques, safety, and diagnostic aspects of these procedures.