3. Hormonal Regulation of Erectile Function, from Basic to Bedside (Androgen, Estrogen, Prolactin, GH, Thyroid Hormones)

  1. Mario Maggi
  1. Annamaria Morelli1,
  2. Linda Vignozzi1 and
  3. Mario Maggi2

Published Online: 29 NOV 2011

DOI: 10.1002/9781119963820.ch3

Hormonal Therapy for Male Sexual Dysfunction

Hormonal Therapy for Male Sexual Dysfunction

How to Cite

Morelli, A., Vignozzi, L. and Maggi, M. (2011) Hormonal Regulation of Erectile Function, from Basic to Bedside (Androgen, Estrogen, Prolactin, GH, Thyroid Hormones), in Hormonal Therapy for Male Sexual Dysfunction (ed M. Maggi), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119963820.ch3

Editor Information

  1. Sexual Medicine & Andrology, University of Florence, Florence, Italy

Author Information

  1. 1

    Department of Clinical Physiopathology, University of Florence, Florence, Italy

  2. 2

    Sexual Medicine & Andrology, University of Florence, Florence, Italy

Publication History

  1. Published Online: 29 NOV 2011
  2. Published Print: 15 DEC 2011

ISBN Information

Print ISBN: 9780470657607

Online ISBN: 9781119963820

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Keywords:

  • Nitric oxide;
  • cyclic-GMP;
  • PDE5;
  • testosterone;
  • smooth muscle cells;
  • hypogonadism;
  • RhoA/ROCK signaling;
  • PDE5 inhibitors;
  • corpora cavernosa;
  • metabolic syndrome

Summary

The recent advances in our knowledge of erectile physiology and of the role played by hormones in the regulatory mechanisms of male sexual function strongly improve the clinical management of men affected by erectile dysfunction (ED). Testosterone is the main hormone involved, acting at both central and peripheral level. Other hormones are also involved, therefore hormonal value assessment is recommended in order to adequately treat ED patients.