15. Modelling Biological Networks via Tailored Random Graphs

  1. Michael P. H. Stumpf4,
  2. David J. Balding5 and
  3. Mark Girolami6
  1. Anthony C. C. Coolen1,2,
  2. Franca Fraternali2,
  3. Alessia Annibale1,
  4. Luis Fernandes2 and
  5. Jens Kleinjung3

Published Online: 12 SEP 2011

DOI: 10.1002/9781119970606.ch15

Handbook of Statistical Systems Biology

Handbook of Statistical Systems Biology

How to Cite

Coolen, A. C. C., Fraternali, F., Annibale, A., Fernandes, L. and Kleinjung, J. (2011) Modelling Biological Networks via Tailored Random Graphs, in Handbook of Statistical Systems Biology (eds M. P. H. Stumpf, D. J. Balding and M. Girolami), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119970606.ch15

Editor Information

  1. 4

    Division of Molecular Biosciences, Imperial College London, UK

  2. 5

    Institute of Genetics, University College London, UK

  3. 6

    Department of Statistical Science, University College London, UK

Author Information

  1. 1

    Department of Mathematics, King's College London, The Strand, London, UK

  2. 2

    Randall Division of Cell and Molecular Biophysics, King's College London, New Hunt's House, London, UK

  3. 3

    Divison of Mathematical Biology, MRC National Institute for Medical Research, London, UK

Publication History

  1. Published Online: 12 SEP 2011
  2. Published Print: 21 OCT 2011

ISBN Information

Print ISBN: 9780470710869

Online ISBN: 9781119970606



  • biological networks via tailored random graphs;
  • network topology characterization;
  • PPIN of H. sapiens;
  • PPIN datasets;
  • network families and random graphs;
  • information-theoretic deliverables;
  • numerical generation;
  • cellular signalling networks


This chapter contains sections titled:

  • Introduction

  • Quantitative characterization of network topologies

  • Network families and random graphs

  • Information-theoretic deliverables of tailored random graphs

  • Applications to PPINs

  • Numerical generation of tailored random graphs

  • Discussion

  • References