23. Host–Pathogen Systems Biology

  1. Michael P. H. Stumpf2,
  2. David J. Balding3 and
  3. Mark Girolami4
  1. John W. Pinney

Published Online: 12 SEP 2011

DOI: 10.1002/9781119970606.ch23

Handbook of Statistical Systems Biology

Handbook of Statistical Systems Biology

How to Cite

Pinney, J. W. (2011) Host–Pathogen Systems Biology, in Handbook of Statistical Systems Biology (eds M. P. H. Stumpf, D. J. Balding and M. Girolami), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119970606.ch23

Editor Information

  1. 2

    Division of Molecular Biosciences, Imperial College London, UK

  2. 3

    Institute of Genetics, University College London, UK

  3. 4

    Department of Statistical Science, University College London, UK

Author Information

  1. Centre for Bioinformatics, Division of Molecular Biosciences, Imperial College London, UK

Publication History

  1. Published Online: 12 SEP 2011
  2. Published Print: 21 OCT 2011

ISBN Information

Print ISBN: 9780470710869

Online ISBN: 9781119970606

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Keywords:

  • host–pathogen systems biology;
  • host–pathogen interactions;
  • host–pathogen systems dynamics;
  • biology of pathogenic organisms;
  • drug target identification;
  • genomic pathogenicity islands;
  • sequence data integration;
  • symbiont metabolic networks;
  • proteome-wide datasets

Summary

This chapter contains sections titled:

  • Introduction

  • Pathogen genomics

  • Metabolic models

  • Protein–protein interactions

  • Response to environment

  • Immune system interactions

  • Manipulation of other host systems

  • Evolution of the host–pathogen system

  • Towards systems medicine for infectious diseases

  • Concluding remarks

  • Acknowledgements

  • References