8. Management of Perioperative Bleeding

  1. Andrea Mozzarelli2,3 and
  2. Stefano Bettati2,3
  1. Sibylle A. Kozek-Langenecker

Published Online: 4 JUL 2011

DOI: 10.1002/9781119975427.ch8

Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood

Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood

How to Cite

Kozek-Langenecker, S. A. (2011) Management of Perioperative Bleeding, in Chemistry and Biochemistry of Oxygen Therapeutics: From Transfusion to Artificial Blood (eds A. Mozzarelli and S. Bettati), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119975427.ch8

Editor Information

  1. 2

    Department of Biochemistry and Molecular Biology, University of Parma, Parma, Italy

  2. 3

    National Institute of Biostructures and Biosystems, Rome, Italy

Author Information

  1. Department of Anesthesia and Intensive Care, Evangelical Hospital Vienna, Vienna, Austria

Publication History

  1. Published Online: 4 JUL 2011
  2. Published Print: 12 AUG 2011

ISBN Information

Print ISBN: 9780470686683

Online ISBN: 9781119975427

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Keywords:

  • perioperative bleeding management;
  • coagulation management and point-of-care tests (POCTs) - for complex bleeding pathomechanisms;
  • coagulopathy pathomechanisms - in massive bleeding;
  • massive transfusion, replacement of one blood volume over 24 hours;
  • coagulopathy, confounded by hypothermia - acidosis, preexisting disorders;
  • perioperative coagulation monitoring - acquired perioperative coagulopathy;
  • routine coagulation tests in perioperative setting, limitations - false differential diagnosis, therapeutic misadventures;
  • thromboelastography (TEG) and rotational thromboelastometry (ROTEM);
  • coagulation management algorithm;
  • transfusion algorithms based on thromboelastographic parameters - reducing transfusion requirements

Summary

This chapter contains sections titled:

  • Introduction

  • Pathomechanisms of Coagulopathy in Massive Bleeding

  • Perioperative Coagulation Monitoring

  • Limitations of Routine Coagulation Tests in the Perioperative Setting

  • Thromboelastography (TEG) and Rotational Thromboelastometry (ROTEM)

  • Procoagulant Interventions

  • Algorithm for Coagulation Management

  • References