9. Chip-Based Proteomics

  1. Ralph Rapley2 and
  2. Stuart Harbron3
  1. Julian Bailes,
  2. Andrew Milnthorpe,
  3. Sandra Smieszek and
  4. Mikhail Soloviev

Published Online: 7 OCT 2011

DOI: 10.1002/9781119977438.ch9

Molecular Analysis and Genome Discovery, Second Edition

Molecular Analysis and Genome Discovery, Second Edition

How to Cite

Bailes, J., Milnthorpe, A., Smieszek, S. and Soloviev, M. (2011) Chip-Based Proteomics, in Molecular Analysis and Genome Discovery, Second Edition (eds R. Rapley and S. Harbron), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119977438.ch9

Editor Information

  1. 2

    University of Hertfordshire, UK

  2. 3

    The Enzyme Technology Consultancy, UK

Author Information

  1. School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey, TW20 0EX, UK

Publication History

  1. Published Online: 7 OCT 2011
  2. Published Print: 4 NOV 2011

ISBN Information

Print ISBN: 9780470758779

Online ISBN: 9781119977438

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Keywords:

  • chip-based proteomics;
  • modern proteomics and ‘multiplexing’;
  • lab-on-a-chip (LOC) approaches;
  • antibody microarrays and fluorescence detection;
  • ZeptoMARKTM array surfaces;
  • reverse-phase protein arrays (RPPA);
  • chip-based mass spectrometry;
  • microfluidics monoclonal antibody-based analysis;
  • protein expression profiling technique, chip format

Summary

This chapter contains sections titled:

  • Introduction

  • Lab-on-a-chip

  • Arrays

  • Chip-based mass spectrometry

  • Surface plasmon resonance (SPR) and quartz crystal microbalance (QCM) chip instruments

  • Microfluidics

  • Conclusion

  • References