1. History of Hemophilia

  1. Emérito-Carlos Rodríguez-Merchán MD, PHD2,3 and
  2. Leonard A. Valentino MD4
  1. Caroline Cromwell MD and
  2. Louis M. Aledort MD

Published Online: 12 MAY 2011

DOI: 10.1002/9781119979401.ch1

Current and Future Issues in Hemophilia Care

Current and Future Issues in Hemophilia Care

How to Cite

Cromwell, C. and Aledort, L. M. (2011) History of Hemophilia, in Current and Future Issues in Hemophilia Care (eds E.-C. Rodríguez-Merchán and L. A. Valentino), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119979401.ch1

Editor Information

  1. 2

    Department of Orthopedic Surgery and Hemophilia Unit, La Paz University Hospital, Spain

  2. 3

    School of Medicine, Autonomous University, Madrid, Spain

  3. 4

    Hemophilia and Thrombophilia Center, Rush University Medical Center, Chicago, IL, USA

Author Information

  1. Mount Sinai School of Medicine, New York, NY, USA

Publication History

  1. Published Online: 12 MAY 2011
  2. Published Print: 13 MAY 2011

ISBN Information

Print ISBN: 9780470670576

Online ISBN: 9781119979401



  • history of hemophilia;
  • hemophilia A;
  • hemophilia B;
  • royal hemophilia


There is a wealth of older literature and historical notations of what would eventually come to be known as hemophilia. This brief introduction will cover the highlights of the history of hemophilia including: (1) evolution of the understanding of its inheritance; (2) origin of the name hemophilia; (3) recognition and isolation of the clotting defect; (4) the evolution of treatment; (5) the future of hemophilia therapy.