2. Hemophilia Care in the Modern World

  1. Emérito-Carlos Rodríguez-Merchán MD, PHD2,3 and
  2. Leonard A. Valentino MD4
  1. Christine A. Lee MA, MD, DSc, FRCP, FRCPath, FRCOG ad eundem

Published Online: 12 MAY 2011

DOI: 10.1002/9781119979401.ch2

Current and Future Issues in Hemophilia Care

Current and Future Issues in Hemophilia Care

How to Cite

Lee, C. A. (2011) Hemophilia Care in the Modern World, in Current and Future Issues in Hemophilia Care (eds E.-C. Rodríguez-Merchán and L. A. Valentino), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119979401.ch2

Editor Information

  1. 2

    Department of Orthopedic Surgery and Hemophilia Unit, La Paz University Hospital, Spain

  2. 3

    School of Medicine, Autonomous University, Madrid, Spain

  3. 4

    Hemophilia and Thrombophilia Center, Rush University Medical Center, Chicago, IL, USA

Author Information

  1. University of London, London, UK

Publication History

  1. Published Online: 12 MAY 2011
  2. Published Print: 13 MAY 2011

ISBN Information

Print ISBN: 9780470670576

Online ISBN: 9781119979401



  • hemophilia;
  • world;
  • aging;
  • prophylaxis;
  • factor concentrate;
  • immunogenicity;
  • women with bleeding disorders


Hemophilia care in the modern world has to embrace many new challenges. Improved diagnosis and care in the world have introduced the new problems of ageing with co-morbidities in addition to a bleeding disorder. Primary prophylaxis is now the accepted treatment for young boys with hemophilia but it needs to be “tailored” and made possible for the less developed world. Production of factor concentrates is responding to the need to provide treatment with prolonged efficacy and reduced immunogenicity. It has been recognized that half the people with inherited bleeding disorders are women who need to be identified and directed to clinical care.