22. Experimental Studies on Hemarthrosis, Synovitis and Arthropathy

  1. Emérito-Carlos Rodríguez-Merchán MD, PHD1,2 and
  2. Leonard A. Valentino MD3
  1. Leonard A. Valentino MD and
  2. Narine Hakobyan PhD

Published Online: 12 MAY 2011

DOI: 10.1002/9781119979401.ch22

Current and Future Issues in Hemophilia Care

Current and Future Issues in Hemophilia Care

How to Cite

Valentino, L. A. and Hakobyan, N. (2011) Experimental Studies on Hemarthrosis, Synovitis and Arthropathy, in Current and Future Issues in Hemophilia Care (eds E.-C. Rodríguez-Merchán and L. A. Valentino), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781119979401.ch22

Editor Information

  1. 1

    Department of Orthopedic Surgery and Hemophilia Unit, La Paz University Hospital, Spain

  2. 2

    School of Medicine, Autonomous University, Madrid, Spain

  3. 3

    Hemophilia and Thrombophilia Center, Rush University Medical Center, Chicago, IL, USA

Author Information

  1. Hemophilia and Thrombophilia Center, Rush University Medical Center, Chicago, IL, USA

Publication History

  1. Published Online: 12 MAY 2011
  2. Published Print: 13 MAY 2011

ISBN Information

Print ISBN: 9780470670576

Online ISBN: 9781119979401

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Keywords:

  • arthropathy;
  • hemophilia;
  • hemarthrosis;
  • joint bleeding;
  • joint damage

Summary

Joint bleeding is a common problem in patients with hemophilia and results in pain, deformity, and disability due to structural damage to muscle, cartilage and bone. The pathogenesis of hemophilic arthropathy is incompletely understood but has similarities to both osteoarthritis (OA) and rheumatoid arthritis (RA). In this chapter, the potential effects of blood on the joint structures will be reviewed in the context of the development of hemophilic arthropathy.