8. Towards a Comprehensive, Causal and Explanatory Neuroscience Model of Anorexia Nervosa

  1. Bryan Lask3,4,5 and
  2. Ian Frampton3,6
  1. Kenneth Nunn1,2,
  2. Bryan Lask3,4,5 and
  3. Ian Frampton3,6

Published Online: 10 JUL 2011

DOI: 10.1002/9781119998402.ch8

Eating Disorders and the Brain

Eating Disorders and the Brain

How to Cite

Nunn, K., Lask, B. and Frampton, I. (2011) Towards a Comprehensive, Causal and Explanatory Neuroscience Model of Anorexia Nervosa, in Eating Disorders and the Brain (eds B. Lask and I. Frampton), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119998402.ch8

Editor Information

  1. 3

    Regional Eating Disorders Service, Oslo University Hospital, Oslo Universitetssykehus HF, Ullevål, Bygg 37, 0407 Oslo, Norway

  2. 4

    Ellern Mede Service for Eating Disorders, 31 Totteridge Common, London, N20 8LR, UK

  3. 5

    Great Ormond Street Hospital for Children, London, WC1N 3JH, UK

  4. 6

    College of Life and Environmental Sciences, University of Exeter, Exeter, EX4 4QG, UK

Author Information

  1. 1

    Molecular Neuropsychiatry Service, Department of Psychological Medicine, The Children's Hospital at Westmead, Westmead, NSW, 2145, Australia

  2. 2

    School of Psychiatry, University of New South Wales, Sydney, 2052, Australia

  3. 3

    Regional Eating Disorders Service, Oslo University Hospital, Oslo Universitetssykehus HF, Ullevål, Bygg 37, 0407 Oslo, Norway

  4. 4

    Ellern Mede Service for Eating Disorders, 31 Totteridge Common, London, N20 8LR, UK

  5. 5

    Great Ormond Street Hospital for Children, London, WC1N 3JH, UK

  6. 6

    College of Life and Environmental Sciences, University of Exeter, Exeter, EX4 4QG, UK

Publication History

  1. Published Online: 10 JUL 2011
  2. Published Print: 26 AUG 2011

ISBN Information

Print ISBN: 9780470670033

Online ISBN: 9781119998402

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Keywords:

  • comprehensive, causal and explanatory neuroscience model - of anorexia nervosa;
  • anorexia nervosa (AN) - phenomenology and maintenance;
  • AN complexity, any explanatory model - being multifaceted;
  • aetiology and maintenance of AN;
  • specific genetic profile, neurobiological substrate - context, of specific sociocultural influences;
  • noradrenergic genetic profile - neurotransmitter systems in AN, and serotonergic mechanisms;
  • Season of birth (SoB), risk factors for AN - findings, of a spring SoB bias;
  • impaired neuroplasticity - nervous system capacity, in modifying its organisation;
  • neuropsychological interventions - cognitive remediation therapy (CRT), and cognitive deficits;
  • consequent body-image distortion - body-focused anxiety, and intense dieting

Summary

This chapter contains sections titled:

  • Introduction

  • The model

  • Critical appraisal

  • Clinical implications

  • Conclusion

  • Acknowledgements

  • References