4. Common Genetic and Neurocutaneous Disorders in Childhood Epilepsy

  1. James W. Wheless
  1. Dewi Frances T. Depositario-Cabacar1,
  2. William McClintock1 and
  3. Tom Reehal2

Published Online: 1 NOV 2012

DOI: 10.1002/9781119998600.ch4

Epilepsy in Children and Adolescents

Epilepsy in Children and Adolescents

How to Cite

Depositario-Cabacar, D. F. T., McClintock, W. and Reehal, T. (2012) Common Genetic and Neurocutaneous Disorders in Childhood Epilepsy, in Epilepsy in Children and Adolescents (ed J. W. Wheless), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119998600.ch4

Editor Information

  1. Department of Pediatric Neurology, University of Tennessee Health Science Center, Le Bonheur Comprehensive Epilepsy Program and Neuroscience Institute, Le Bonheur Children's Hospital, Memphis, TN, USA

Author Information

  1. 1

    Neurology and Pediatrics, George Washington University Medical Center, Children's National Medical Center, Washington, DC, USA

  2. 2

    University of Sheffield School of Medicine, Dentistry, and Health, Sheffield, UK

Publication History

  1. Published Online: 1 NOV 2012
  2. Published Print: 23 NOV 2012

ISBN Information

Print ISBN: 9780470741238

Online ISBN: 9781119998600

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Keywords:

  • genetics;
  • epilepsy;
  • neurocutaneousdisorders;
  • pediatrics

Summary

Genetic studies on epilepsy play a significant role in improving early diagnosis, avoiding ordering of unnecessary tests, selecting the appropriate antiepileptic medication, and providing information on prognosis and recurrence risk. Some of the more common genetic and neurocutaneous disorders are discussed in this chapter. Specifically, the genes identified in some of the more common idiopathic epilepsy syndromes are discussed. A few of the symptomatic epilepsies, which include the neurocutaneous disorders, neuronal migration disorders, chromosomal abnormalities, inborn errors of metabolism, and mitochondrial disorders, are also reviewed.