5. Reward Processing

  1. Bryon Adinoff3,4 and
  2. Elliot A. Stein5
  1. Anne Beck1,
  2. Anthony A. Grace2 and
  3. Andreas Heinz1

Published Online: 2 NOV 2011

DOI: 10.1002/9781119998938.ch5

Neuroimaging in Addiction

Neuroimaging in Addiction

How to Cite

Beck, A., Grace, A. A. and Heinz, A. (2011) Reward Processing, in Neuroimaging in Addiction (eds B. Adinoff and E. A. Stein), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119998938.ch5

Editor Information

  1. 3

    Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA

  2. 4

    VA North Texas Health Care System, Dallas, TX, USA

  3. 5

    National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA

Author Information

  1. 1

    Department of Psychiatry and Psychotherapy Charité, Universitätsmedizin Berlin Charité Campus Mitte Charitéplatz 1, Berlin, Germany

  2. 2

    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, USA

Publication History

  1. Published Online: 2 NOV 2011
  2. Published Print: 9 NOV 2011

ISBN Information

Print ISBN: 9780470660140

Online ISBN: 9781119998938



  • reward processing;
  • addictions, processing of reward;
  • drug-related rewards;
  • ventral striatum activation;
  • “sign-trackers,” psychomotor sensitization;
  • blood oxygen level dependent (BOLD) fMRI;
  • dopaminergic neurotransmission dysfunction;
  • model, conditioned drug and alcohol craving;
  • “cue-reactivity” paradigms;
  • striatal dopaminergic signaling


This chapter contains sections titled:

  • Introduction

  • Neurotransmitter Systems Implicated in Reward Processing

  • Neurotransmitter Systems Involved in Drug-Related Reward Processing

  • Alterations in the Mesostriatal System in Addiction

  • Summary and Outlook

  • Acknowledgments

  • References