8. Cognitive Disruptions in Drug Addiction: A Focus on the Prefrontal Cortex

  1. Bryon Adinoff4,5 and
  2. Elliot A. Stein6
  1. Rita Z. Goldstein1,
  2. Scott J. Moeller1 and
  3. Nora D. Volkow2,3

Published Online: 2 NOV 2011

DOI: 10.1002/9781119998938.ch8

Neuroimaging in Addiction

Neuroimaging in Addiction

How to Cite

Goldstein, R. Z., Moeller, S. J. and Volkow, N. D. (2011) Cognitive Disruptions in Drug Addiction: A Focus on the Prefrontal Cortex, in Neuroimaging in Addiction (eds B. Adinoff and E. A. Stein), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9781119998938.ch8

Editor Information

  1. 4

    Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA

  2. 5

    VA North Texas Health Care System, Dallas, TX, USA

  3. 6

    National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA

Author Information

  1. 1

    Medical Research, Brookhaven National Laboratory, Upton, NY, USA

  2. 2

    National Institute on Alcohol & Alcoholism, Bethesda, MD, USA

  3. 3

    National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA

Publication History

  1. Published Online: 2 NOV 2011
  2. Published Print: 9 NOV 2011

ISBN Information

Print ISBN: 9780470660140

Online ISBN: 9781119998938

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Keywords:

  • drug addiction, cognitive disruptions;
  • neurocognitive disruptions;
  • functional magnetic resonance (fMRI);
  • dorsolateral prefrontal cortex (DLPFC);
  • attention;
  • attention without drug administration;
  • visual attention enhanced by nicotine;
  • working memory (WM);
  • popular WM task, N-back task;
  • pre-morbid vulnerabilities

Summary

This chapter contains sections titled:

  • Introduction

  • Attention

  • Working Memory

  • Decision-Making

  • Pre-Morbid Vulnerabilities

  • Other Brain Regions

  • Limitations Across All Studies

  • Treatment Implications

  • General Summary and Conclusions

  • Acknowledgments

  • References