Chapter 21. Molecular, Biochemical, and Metabolic Abnormalities of Acute Pancreatitis

  1. Hans G. Beger MD, FACS(Hon) Founding Editor Emeritus Professor of Surgery2,
  2. Andrew L. Warshaw MD Surgeon-in-Chief Chairman3,4,
  3. Markus W. Büchler MD Chairman Head Professor of Surgery5,
  4. Richard A. Kozarek MD Director6,
  5. Markus M. Lerch MD, FRCP Professor Chair7,
  6. John P. Neoptolemos MA, MB, BChir, MD, FRCS, FMedSci Head Professor of Surgery8,9,10,
  7. Keiko Shiratori MD Chair Professor11,
  8. David C. Whitcomb MD, PhD Professor of Medicine Chief12 and
  9. Bettina M. Rau MD Coordinating Editor Associate Professor of Surgery13
  1. Julia Mayerle MD7,
  2. F. Ulrich Weiss,
  3. Walter Halangk PhD1 and
  4. Markus M. Lerch MD, FRCP Professor Chair7

Published Online: 4 FEB 2009

DOI: 10.1002/9781444300123.ch21

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

How to Cite

Mayerle, J., Weiss, F. U., Halangk, W. and Lerch, M. M. (2008) Molecular, Biochemical, and Metabolic Abnormalities of Acute Pancreatitis, in The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition (eds H. G. Beger, A. L. Warshaw, M. W. Büchler, R. A. Kozarek, M. M. Lerch, J. P. Neoptolemos, K. Shiratori, D. C. Whitcomb and B. M. Rau), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444300123.ch21

Editor Information

  1. 2

    c/o Universitätsklinikum Ulm, University of Ulm, Germany

  2. 3

    Department of Surgery, Massachusetts General Hospital, Boston, MA, USA

  3. 4

    W. Gerald Austen Professor of Surgery, Harvard Medical School, Boston, MA, USA

  4. 5

    Department of General and Visceral Surgery, University of Heidelberg, Germany

  5. 6

    Digestive Disease Institute, Virginia Mason Medical Center, Seattle, WA, USA

  6. 7

    Department of Gastroenterology, Endocrinology and Nutrition, Ernst-Moritz-Arndt University, Greifswald, Germany

  7. 8

    The Owen and Ellen Evans Chair of Cancer Studies, University of Liverpool, UK

  8. 9

    Division of Surgery and Oncology, University of Liverpool, UK

  9. 10

    School of Cancer Studies, University of Liverpool, UK

  10. 11

    Department of Gastroenterology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan

  11. 12

    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, PA, USA

  12. 13

    Department of General, Thoracic, Vascular and Transplantation Surgery, University of Rostock, Germany

Author Information

  1. 1

    Department of Experimental Surgery, Otto-von-Guericke University, Magdeburg, Germany

  2. 7

    Department of Gastroenterology, Endocrinology and Nutrition, Ernst-Moritz-Arndt University, Greifswald, Germany

Publication History

  1. Published Online: 4 FEB 2009
  2. Published Print: 11 APR 2008

ISBN Information

Print ISBN: 9781405146647

Online ISBN: 9781444300123

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Keywords:

  • molecular and biochemical abnormalities;
  • Pancreatic secretory trypsin inhibitor (PSTI);
  • systemic inflammatory response syndrome (SIRS);
  • MARS (mixed antiinflammatory response syndrome);
  • digestive protease activation;
  • paralytic ileus and gut permeability pathogenesis;
  • cell biological and molecular techniques;
  • metabolic and systemic abnormalities;
  • hypocalcemia and hypomagnesemia

Summary

This chapter contains sections titled:

  • Introduction

  • Molecular and biochemical abnormalities

  • Metabolic and systemic abnormalities

  • Role of hypocalcemia and hypomagnesemia

  • References