Chapter 39. Epidemiology and Pathophysiology of Alcoholic Chronic Pancreatitis

  1. Hans G. Beger MD, FACS(Hon) Founding Editor Emeritus Professor of Surgery4,
  2. Andrew L. Warshaw MD Surgeon-in-Chief Chairman5,6,
  3. Markus W. Büchler MD Chairman Head Professor of Surgery7,
  4. Richard A. Kozarek MD Director8,
  5. Markus M. Lerch MD, FRCP Professor Chair9,
  6. John P. Neoptolemos MA, MB, BChir, MD, FRCS, FMedSci Head Professor of Surgery10,11,12,
  7. Keiko Shiratori MD Chair Professor13,
  8. David C. Whitcomb MD, PhD Professor of Medicine Chief14 and
  9. Bettina M. Rau MD Coordinating Editor Associate Professor of Surgery15
  1. Stephen J. Pandol MD Professor of Medicine Director of Pancreatic Research Group Staff Physician1,2,
  2. Aurelia Lugea,
  3. Anna S. Gukovskaya PhD Adjunct Professor Co-director of Pancreatic Research Group1,2 and
  4. Ilya Gukovsky MD3

Published Online: 4 FEB 2009

DOI: 10.1002/9781444300123.ch39

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

How to Cite

Pandol, S. J., Lugea, A., Gukovskaya, A. S. and Gukovsky, I. (2009) Epidemiology and Pathophysiology of Alcoholic Chronic Pancreatitis, in The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition (eds H. G. Beger, A. L. Warshaw, M. W. Büchler, R. A. Kozarek, M. M. Lerch, J. P. Neoptolemos, K. Shiratori, D. C. Whitcomb and B. M. Rau), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444300123.ch39

Editor Information

  1. 4

    c/o Universitätsklinikum Ulm, University of Ulm, Germany

  2. 5

    Department of Surgery, Massachusetts General Hospital, Boston, MA, USA

  3. 6

    W. Gerald Austen Professor of Surgery, Harvard Medical School, Boston, MA, USA

  4. 7

    Department of General and Visceral Surgery, University of Heidelberg, Germany

  5. 8

    Digestive Disease Institute, Virginia Mason Medical Center, Seattle, WA, USA

  6. 9

    Department of Gastroenterology, Endocrinology and Nutrition, Ernst-Moritz-Arndt University, Greifswald, Germany

  7. 10

    The Owen and Ellen Evans Chair of Cancer Studies, University of Liverpool, UK

  8. 11

    Division of Surgery and Oncology, University of Liverpool, UK

  9. 12

    School of Cancer Studies, University of Liverpool, UK

  10. 13

    Department of Gastroenterology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan

  11. 14

    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, PA, USA

  12. 15

    Department of General, Thoracic, Vascular and Transplantation Surgery, University of Rostock, Germany

Author Information

  1. 1

    University of California at Los Angeles, CA, USA

  2. 2

    VA Greater Los Angeles Health Care System, CA, USA

  3. 3

    Pancreatic Research Group, University of California at Los Angeles and VA Greater Los Angeles Health Care System, CA, USA

Publication History

  1. Published Online: 4 FEB 2009
  2. Published Print: 11 APR 2008

ISBN Information

Print ISBN: 9781405146647

Online ISBN: 9781444300123

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Keywords:

  • alcohol-induced chronic pancreatitis - epidemiology and pathophysiology;
  • chronic pancreatitis and alcohol abuse;
  • smoking, dietary factors and alcoholic chronic pancreatitis risk;
  • alcohol and inflammatory response of pancreatitis;
  • pancreatic stellate cells and chronic pancreatitis;
  • transforming growth factor (TGF)-β and platelet-derived growth factor (PDGF);
  • chronic pancreatitis and plasminogen system;
  • matrix metalloproteinases (MMPs)

Summary

This chapter contains sections titled:

  • Epidemiology

  • Pathobiology

  • Pancreatic stellate cells and chronic pancreatitis

  • The plasminogen system in chronic pancreatitis

  • Summary

  • References