Chapter 64. Screening of Hereditary Pancreatic Cancer Families

  1. Hans G. Beger MD, FACS(Hon) Founding Editor Emeritus Professor of Surgery2,
  2. Andrew L. Warshaw MD Surgeon-in-Chief Chairman3,4,
  3. Markus W. Büchler MD Chairman Head Professor of Surgery5,
  4. Richard A. Kozarek MD Director6,
  5. Markus M. Lerch MD, FRCP Professor Chair7,
  6. John P. Neoptolemos MA, MB, BChir, MD, FRCS, FMedSci Head Professor of Surgery8,9,10,
  7. Keiko Shiratori MD Chair Professor11,
  8. David C. Whitcomb MD, PhD Professor of Medicine Chief12 and
  9. Bettina M. Rau MD Coordinating Editor Associate Professor of Surgery13
  1. Christopher Carlson MD1,
  2. William Greenhalf PhD Lecturer in Molecular Biology9 and
  3. Teresa A. Brentnall MD Associate Professor Gastroenterology1

Published Online: 4 FEB 2009

DOI: 10.1002/9781444300123.ch64

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

How to Cite

Carlson, C., Greenhalf, W. and Brentnall, T. A. (2009) Screening of Hereditary Pancreatic Cancer Families, in The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition (eds H. G. Beger, A. L. Warshaw, M. W. Büchler, R. A. Kozarek, M. M. Lerch, J. P. Neoptolemos, K. Shiratori, D. C. Whitcomb and B. M. Rau), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444300123.ch64

Editor Information

  1. 2

    c/o Universitätsklinikum Ulm, University of Ulm, Germany

  2. 3

    Department of Surgery, Massachusetts General Hospital, Boston, MA, USA

  3. 4

    W. Gerald Austen Professor of Surgery, Harvard Medical School, Boston, MA, USA

  4. 5

    Department of General and Visceral Surgery, University of Heidelberg, Germany

  5. 6

    Digestive Disease Institute, Virginia Mason Medical Center, Seattle, WA, USA

  6. 7

    Department of Gastroenterology, Endocrinology and Nutrition, Ernst-Moritz-Arndt University, Greifswald, Germany

  7. 8

    The Owen and Ellen Evans Chair of Cancer Studies, University of Liverpool, UK

  8. 9

    Division of Surgery and Oncology, University of Liverpool, UK

  9. 10

    School of Cancer Studies, University of Liverpool, UK

  10. 11

    Department of Gastroenterology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan

  11. 12

    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, PA, USA

  12. 13

    Department of General, Thoracic, Vascular and Transplantation Surgery, University of Rostock, Germany

Author Information

  1. 1

    University of Washington Medical Center, Seattle, WA, USA

  2. 9

    Division of Surgery and Oncology, University of Liverpool, UK

Publication History

  1. Published Online: 4 FEB 2009
  2. Published Print: 11 APR 2008

ISBN Information

Print ISBN: 9781405146647

Online ISBN: 9781444300123

SEARCH

Keywords:

  • familial pancreatic cancer kindreds;
  • National Familial Pancreatic Tumor Registry (NFPTR);
  • familial atypical multiple mole melanoma (FAMMM) syndrome;
  • hereditary pancreatitis;
  • p16INK4a tumor-suppressor gene;
  • pancreatic cancer surveillance program;
  • EUROPAC proposal for hereditary pancreatitis;
  • EUROPAC FPC cohort

Summary

This chapter contains sections titled:

  • Introduction

  • Familial pancreatic cancer kindreds

  • Hereditary pancreatitis

  • Polyposis and nonpolyposis colon cancer syndromes

  • Familial atypical multiple mole melanoma syndrome

  • Histopathology of pancreatic cancer and precancer

  • Screening

  • Pancreatic cancer surveillance programs

  • Surgical management

  • Cost-effectiveness of surveillance

  • Risk factors for cancer

  • References