Chapter 94. Adenoma and Adenocarcinoma of the Ampulla of Vater: Diagnosis and Management

  1. Hans G. Beger MD, FACS(Hon) Founding Editor Emeritus Professor of Surgery2,
  2. Andrew L. Warshaw MD Surgeon-in-Chief Chairman3,4,
  3. Markus W. Büchler MD Chairman Head Professor of Surgery5,
  4. Richard A. Kozarek MD Director6,
  5. Markus M. Lerch MD, FRCP Professor Chair7,
  6. John P. Neoptolemos MA, MB, BChir, MD, FRCS, FMedSci Head Professor of Surgery8,9,10,
  7. Keiko Shiratori MD Chair Professor11,
  8. David C. Whitcomb MD, PhD Professor of Medicine Chief12 and
  9. Bettina M. Rau MD Coordinating Editor Associate Professor of Surgery13
  1. William R. Brugge MD1 and
  2. Andrew L. Warshaw MD Surgeon-in-Chief Chairman3,4

Published Online: 4 FEB 2009

DOI: 10.1002/9781444300123.ch94

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition

How to Cite

Brugge, W. R. and Warshaw, A. L. (2009) Adenoma and Adenocarcinoma of the Ampulla of Vater: Diagnosis and Management, in The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery, Second Edition (eds H. G. Beger, A. L. Warshaw, M. W. Büchler, R. A. Kozarek, M. M. Lerch, J. P. Neoptolemos, K. Shiratori, D. C. Whitcomb and B. M. Rau), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444300123.ch94

Editor Information

  1. 2

    c/o Universitätsklinikum Ulm, University of Ulm, Germany

  2. 3

    Department of Surgery, Massachusetts General Hospital, Boston, MA, USA

  3. 4

    W. Gerald Austen Professor of Surgery, Harvard Medical School, Boston, MA, USA

  4. 5

    Department of General and Visceral Surgery, University of Heidelberg, Germany

  5. 6

    Digestive Disease Institute, Virginia Mason Medical Center, Seattle, WA, USA

  6. 7

    Department of Gastroenterology, Endocrinology and Nutrition, Ernst-Moritz-Arndt University, Greifswald, Germany

  7. 8

    The Owen and Ellen Evans Chair of Cancer Studies, University of Liverpool, UK

  8. 9

    Division of Surgery and Oncology, University of Liverpool, UK

  9. 10

    School of Cancer Studies, University of Liverpool, UK

  10. 11

    Department of Gastroenterology, Tokyo Women's Medical University School of Medicine, Tokyo, Japan

  11. 12

    Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh, PA, USA

  12. 13

    Department of General, Thoracic, Vascular and Transplantation Surgery, University of Rostock, Germany

Author Information

  1. 1

    GI Unit, Massachusetts General Hospital, Boston, MA, USA

  2. 3

    Department of Surgery, Massachusetts General Hospital, Boston, MA, USA

  3. 4

    W. Gerald Austen Professor of Surgery, Harvard Medical School, Boston, MA, USA

Publication History

  1. Published Online: 4 FEB 2009
  2. Published Print: 11 APR 2008

ISBN Information

Print ISBN: 9781405146647

Online ISBN: 9781444300123

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Keywords:

  • ampullary malignancies;
  • markers of neoplasia;
  • adenoma and adenocarcinoma of ampulla of vater - diagnosis and management;
  • high-grade neuroendocrine ampullary tumors;
  • EUS staging of ampullary malignancy;
  • endoscopic ablation therapy;
  • carcinoembryonic antigen (CEA);
  • Whipple resection

Summary

This chapter contains sections titled:

  • Introduction

  • Pathogenesis

  • Clinical presentation

  • Histology (Table 94.2)

  • Rare tumors of the ampulla: neuroendocrine tumors

  • Diagnosis and staging of ampullary malignancy

  • Endoscopic management

  • Surgical management (Table 94.4)

  • Recurrence

  • Chemotherapy

  • Summary (Table 94.5)

  • References