Chapter 50. Melasma

  1. Hywel Williams MSC, PhD, FRCP Professor Dermato-Epidemiology Co-ordinating Editor
  1. Asad Salim MRCP1,
  2. Mónica Rengifo-Pardo MD Specialist in Dermatology2,
  3. Sam Vincent MSc Head of Information3 and
  4. Luis Gabriel Cuervo-Amore MD, MSc4

Published Online: 14 JAN 2009

DOI: 10.1002/9781444300161.ch50

Evidence-Based Dermatology, Second Edition

Evidence-Based Dermatology, Second Edition

How to Cite

Salim, A., Rengifo-Pardo, M., Vincent, S. and Cuervo-Amore, L. G. (2009) Melasma, in Evidence-Based Dermatology, Second Edition (ed H. Williams), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444300161.ch50

Editor Information

  1. Centre of Evidence-Based Dermatology, Nottingham University Hospital NHS Trust, Queen's Medical Centre, Nottingham, UK

Author Information

  1. 1

    Dermatology Department, Mid Staffordshire Hospitals, Staffordshire, UK

  2. 2

    Member of the Cochrane Skin Group, Kensington, Maryland, USA

  3. 3

    InferMed Ltd, London, UK

  4. 4

    Pan American Health Organization (PAHO/WHO), Washington, DC, USA

Publication History

  1. Published Online: 14 JAN 2009
  2. Published Print: 11 APR 2008

ISBN Information

Print ISBN: 9781405145183

Online ISBN: 9781444300161



  • melasma - acquired increased skin pigmentation;
  • melasma as pregnancy occurrence;
  • melasma - clinical diagnosis;
  • Melasma Area and Severity Index (MASI);
  • Melasma Area and Melanin Index (MAMI);
  • clinical practice/categorization implications;
  • combined therapies;
  • oral vitamins C and E combination - effective therapy


This chapter contains sections titled:

  • Background

  • Questions

  • Implications of the available evidence

  • References