Chapter 8. Appraising Systematic Reviews and Meta-Analyses

  1. Hywel Williams MSC, PhD, FRCP Professor Dermato-Epidemiology Co-ordinating Editor
  1. Michael Bigby MD Associate Professor of Dermatology1,2 and
  2. Hywel Williams MSC, PhD, FRCP Professor Dermato-Epidemiology Co-ordinating Editor3

Published Online: 14 JAN 2009

DOI: 10.1002/9781444300161.ch8

Evidence-Based Dermatology, Second Edition

Evidence-Based Dermatology, Second Edition

How to Cite

Bigby, M. and Williams, H. (2008) Appraising Systematic Reviews and Meta-Analyses, in Evidence-Based Dermatology, Second Edition (ed H. Williams), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444300161.ch8

Editor Information

  1. Centre of Evidence-Based Dermatology, Nottingham University Hospital NHS Trust, Queen's Medical Centre, Nottingham, UK

Author Information

  1. 1

    Department of Dermatology, Harvard Medical School, Boston, MA, USA

  2. 2

    Beth Israel, Deaconess Medical Center, Boston, MA, USA

  3. 3

    Centre of Evidence-Based Dermatology, Nottingham University Hospital NHS Trust, Queen's Medical Centre, Nottingham, UK

Publication History

  1. Published Online: 14 JAN 2009
  2. Published Print: 11 APR 2008

ISBN Information

Print ISBN: 9781405145183

Online ISBN: 9781444300161

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Keywords:

  • systematic review appraisal and meta-analyses;
  • systematic review and specific clinical questions;
  • systematic review - critical appraisal;
  • Cochrane Controlled Trials Registry (CCTR);
  • publication bias and “positive” effects;
  • pooling results;
  • random-effects models

Summary

This chapter contains sections titled:

  • Introduction

  • Asking a clear question

  • Sources of evidence within a systematic review

  • The hazards of “quick” searches

  • Publication bias

  • Data abstraction

  • Pooling results

  • References