Chapter 9. How to Critically Appraise a Randomized Controlled Trial

  1. Hywel Williams MSC, PhD, FRCP Professor Dermato-Epidemiology Co-ordinating Editor
  1. Hywel Williams MSC, PhD, FRCP Professor Dermato-Epidemiology Co-ordinating Editor

Published Online: 14 JAN 2009

DOI: 10.1002/9781444300161.ch9

Evidence-Based Dermatology, Second Edition

Evidence-Based Dermatology, Second Edition

How to Cite

Williams, H. (2008) How to Critically Appraise a Randomized Controlled Trial, in Evidence-Based Dermatology, Second Edition (ed H. Williams), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444300161.ch9

Editor Information

  1. Centre of Evidence-Based Dermatology, Nottingham University Hospital NHS Trust, Queen's Medical Centre, Nottingham, UK

Author Information

  1. Centre of Evidence-Based Dermatology, Nottingham University Hospital NHS Trust, Queen's Medical Centre, Nottingham, UK

Publication History

  1. Published Online: 14 JAN 2009
  2. Published Print: 11 APR 2008

ISBN Information

Print ISBN: 9781405145183

Online ISBN: 9781444300161

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Keywords:

  • quality and randomized controlled trials (RCTs);
  • treatment allocation - generation and concealment;
  • blinding (masking) intervention;
  • reducing bias and intention-to-treat (ITT) analysis;
  • faulty reporting and faulty trial methods;
  • data dredging;
  • similarity of groups for baseline differences;
  • Consolidated Standards of Reported Trials (CONSORT) statement

Summary

This chapter contains sections titled:

  • The place of randomized controlled trials

  • Definitions of quality, validity, and bias

  • How to tell a good dermatological RCT from a bad one

  • References