Chapter 5. The Diagnostic Before–After Study to Assess Clinical Impact

  1. J. André Knottnerus MD, PhD Professor of General Practice President4,5 and
  2. Frank Buntinx MD, PhD Professor6,7,8
  1. J. André Knottnerus MD, PhD Professor of General Practice President4,5,
  2. Geert-Jan Dinant MD, PhD Professor1,2 and
  3. Onno P. van Schayck Professor of Preventive Medicine Scientific Co-director Research School Caphri3

Published Online: 2 FEB 2009

DOI: 10.1002/9781444300574.ch5

The Evidence Base of Clinical Diagnosis: Theory and methods of diagnostic research, Second Edition

The Evidence Base of Clinical Diagnosis: Theory and methods of diagnostic research, Second Edition

How to Cite

Knottnerus, J. A., Dinant, G.-J. and van Schayck, O. P. (2008) The Diagnostic Before–After Study to Assess Clinical Impact, in The Evidence Base of Clinical Diagnosis: Theory and methods of diagnostic research, Second Edition (eds J. A. Knottnerus and F. Buntinx), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444300574.ch5

Editor Information

  1. 4

    Netherlands School of Primary Care Research, Maastricht University, The Hague, The Netherlands

  2. 5

    The Health Council of The Netherlands, The Hague, The Netherlands

  3. 6

    Department of General Practice, Catholic University Leuven, Belgium

  4. 7

    Netherlands School of Primary Care Research, Maastricht University, Maastricht, The Netherlands

  5. 8

    Department of General Practice, Maastricht University, Maastricht, The Netherlands

Author Information

  1. 1

    Clinical Research in General Practice, Maastricht University, Maastricht, The Netherlands

  2. 2

    School for Public Health and Primary Care (Caphri), Maastricht University, Maastricht, The Netherlands

  3. 3

    Maastricht University, Maastricht, The Netherlands

  4. 4

    Netherlands School of Primary Care Research, Maastricht University, The Hague, The Netherlands

  5. 5

    The Health Council of The Netherlands, The Hague, The Netherlands

Publication History

  1. Published Online: 2 FEB 2009
  2. Published Print: 10 OCT 2008

ISBN Information

Print ISBN: 9781405157872

Online ISBN: 9781444300574

SEARCH

Keywords:

  • diagnostic before–after study;
  • pre- and posttest diagnostic assessment in ESR impact;
  • point of departure - clinical problem with doctor's assessment;
  • diagnostic testing effect on patient's health outcome;
  • performing diagnostic procedure under study and outcome after baseline assessment;
  • posttest outcome;
  • sample size requirements for before–after study design;
  • uncontrollable bias in all phases of study

Summary

This chapter contains sections titled:

  • Introduction

  • The research question

  • Working out the study

  • Concluding remarks

  • References