Chapter 20. Moyamoya Disease

  1. Dr Jong S. Kim MD, PhD2,
  2. Dr Louis R. Caplan MD3 and
  3. Dr K. S. Lawrence Wong MD4
  1. Dr Susumu Miyamoto MD, PhD1,
  2. Jun C. Takahashi MD, PhD1 and
  3. Dr Jong S. Kim MD, PhD2

Published Online: 12 FEB 2009

DOI: 10.1002/9781444300673.ch20

Intracranial Atherosclerosis

Intracranial Atherosclerosis

How to Cite

Miyamoto, S., Takahashi, J. C. and Kim, J. S. (2008) Moyamoya Disease, in Intracranial Atherosclerosis (eds J. S. Kim, L. R. Caplan and K. S. L. Wong), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444300673.ch20

Editor Information

  1. 2

    Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

  2. 3

    Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

  3. 4

    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince Wales Hospital, Hong Kong, People's Republic of China

Author Information

  1. 1

    Department of Neurosurgery, National Cardiovascular Center, Suita, Osaka, Japan

  2. 2

    Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea

Publication History

  1. Published Online: 12 FEB 2009
  2. Published Print: 24 OCT 2008

ISBN Information

Print ISBN: 9781405178228

Online ISBN: 9781444300673

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Keywords:

  • Moyamoya disease (MMD) - occlusion of major arteries of anterior circulation;
  • posterior cerebral artery (PCA);
  • epidemiology of MMD;
  • tissue inhibitor of metalloproteinase (TIMP) gene;
  • MMD clinical presentations - TIA, ischemic stroke, hemorrhagic stroke, seizures, cognitive impairment;
  • non-surgical treatment and managed with anitplatelet agents;
  • Single-photon emission CT (SPECT) and measuring regional cerebral blood flow (rCBF);
  • superficial temporal artery-to-middle cerebral artery (STA–MCA) anastomosis;
  • bypass surgery for hemorrhagic Moyamoya disease

Summary

This chapter contains sections titled:

  • Epidemiology

  • Pathology and pathogenesis

  • Clinical features

  • Diagnosis

  • Non-surgical Treatment

  • Surgical treatment

  • Prognosis

  • References