Chapter 8. Comparing Survival Curves

  1. David Machin1,2,3,
  2. Michael J. Campbell3,
  3. Say Beng Tan4,5 and
  4. Sze Huey Tan2

Published Online: 30 JAN 2009

DOI: 10.1002/9781444300710.ch8

Sample Size Tables for Clinical Studies, Third Edition

Sample Size Tables for Clinical Studies, Third Edition

How to Cite

Machin, D., Campbell, M. J., Tan, S. B. and Tan, S. H. (2008) Comparing Survival Curves, in Sample Size Tables for Clinical Studies, Third Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444300710.ch8

Author Information

  1. 1

    Children's Cancer and Leukaemia Group, University of Leicester, UK

  2. 2

    Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre, Singapore

  3. 3

    Medical Statistics Unit, School of Health and Related Sciences, University of Sheffield, UK

  4. 4

    Singapore Clinical Research Institute, Singapore

  5. 5

    Duke–NUS Graduate Medical School, Singapore

Publication History

  1. Published Online: 30 JAN 2009
  2. Published Print: 21 NOV 2008

ISBN Information

Print ISBN: 9781405146500

Online ISBN: 9781444300710



  • survival curve comparison;
  • endpoint of interest - ‘survival’;
  • ratio of risks of death in two groups - hazard ratio (HR);
  • Logrank test;
  • Exponential distribution for survival time distribution;
  • competing risks;
  • Examples and use of tables;
  • critical events for comparison of survival rates (Logrank test)


This chapter contains sections titled:

  • Introduction

  • Theory and formulae

  • Competing risks

  • Bibliography

  • Examples and use of the tables

  • References