Chapter 11. 5HT3 Antagonists

  1. Gary J. McCleane MD, FFARCSI, DA, DipIMC, Dip Pain Mang Consultant in Pain Management

Published Online: 30 JAN 2009

DOI: 10.1002/9781444300796.ch11

Pain Management: Expanding the Pharmacological Options

Pain Management: Expanding the Pharmacological Options

How to Cite

McCleane, G. J. (2009) 5HT3 Antagonists, in Pain Management: Expanding the Pharmacological Options, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444300796.ch11

Author Information

  1. Rampark Pain Centre, Lurgan, Northern Ireland, Ireland

Publication History

  1. Published Online: 30 JAN 2009
  2. Published Print: 6 JUN 2008

ISBN Information

Print ISBN: 9781405178235

Online ISBN: 9781444300796

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Keywords:

  • 5HT3 antagonists;
  • 5HT3 antagonists in postoperative nausea and vomiting management;
  • Neurokinin-1 expressing neurons (NK-1) in superficial lamina spinal dorsal horn;
  • 5HT3 antagonist tropisetron for reduced pain in fibromyalgia;
  • irritable bowel syndrome;
  • 5HT3 antagonist alosetron for women in diarrhea preponderant irritable bowel syndrome;
  • local tender spot injection;
  • pain caused by injection of irritant substances;
  • metastatic bone pain

Summary

This chapter contains sections titled:

  • The 5HT3 antagonists

  • Neuropathic pain

  • Fibromyalgia

  • Irritable bowel syndrome

  • Local tender spot injection

  • Pain caused by injection of irritant substances

  • Metastatic bone pain

  • Opioid tolerance

  • Clinical use of 5HT3 antagonists

  • Conclusions

  • Bibliography