Chapter 12. Cholecystokinin Antagonists
Published Online: 30 JAN 2009
DOI: 10.1002/9781444300796.ch12
Copyright © 2008 Gary J. McCleane
Book Title
Pain Management: Expanding the Pharmacological Options
Additional Information
How to Cite
McCleane, G. J. (2009) Cholecystokinin Antagonists, in Pain Management: Expanding the Pharmacological Options, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444300796.ch12
Publication History
- Published Online: 30 JAN 2009
- Published Print: 6 JUN 2008
ISBN Information
Print ISBN: 9781405178235
Online ISBN: 9781444300796
- Summary
- Chapter
Keywords:
- cholecystokinin in nervous system;
- cholecystokinin as anti-opioid peptide;
- cholecystokinin antagonists;
- CCK antagonist enhancing antinociceptive effect of opioid;
- CCK antagonists on antinociceptive tolerance to opioids;
- reversal of established tolerance;
- safety of CCK antagonists
Summary
This chapter contains sections titled:
Cholecystokinin
Role of cholecystokinin in the nervous system
Cholecystokinin as an anti-opioid peptide
Cholecystokinin antagonists
Effect of CCK antagonists on opioid-derived antinociception
Effect of CCK antagonists on antinociceptive tolerance to opioids
Reversal of established tolerance
Safety of CCK antagonists
Human studies
Other potential effects of CCK antagonists
Human use
Conclusions
Bibliography