Chapter 26. Neutropenia

  1. Mark A. Crowther MD, MSc, FRCPC Professor Division Director2,3,
  2. Jeff Ginsberg MD, FRCPC Professor4,
  3. Holger J. Schünemann MD, PhD, MSc, FACP, FCCP Professor5,6,
  4. Ralph M. Meyer MD, FRCPC Director Professor7,8 and
  5. Richard Lottenberg MD, FACP Professor9
  1. David C. Dale MD, FACP

Published Online: 4 FEB 2009

DOI: 10.1002/9781444300857.ch26

Evidence-Based Hematology

Evidence-Based Hematology

How to Cite

Dale, D. C. (2008) Neutropenia, in Evidence-Based Hematology (eds M. A. Crowther, J. Ginsberg, H. J. Schünemann, R. M. Meyer and R. Lottenberg), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444300857.ch26

Editor Information

  1. 2

    Division of Hematology, McMaster University, Hamilton, Ontario, Canada

  2. 3

    St. Joseph's Hospital, Hamilton, Ontario, Canada

  3. 4

    Department of Medicine, McMaster University, Hamilton, Canada

  4. 5

    CLARITY Research Group, Department of Epidemiology, Italian National Cancer Institute Regina Elena, Rome, Italy

  5. 6

    McMaster University, Hamilton, Canada

  6. 7

    National Cancer Institute of Canada, Clinical Trials Group, Edith Eisenhauer Chair in Clinical Cancer Research, Queen's University, Kingston, Ontario, Canada

  7. 8

    Departments of Oncology and Medicine, Queen's University, Kingston, Ontario, Canada

  8. 9

    Division of Hematology/Oncology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA

Author Information

  1. Department of Medicine, University of Washington, Seattle, Washington, USA

Publication History

  1. Published Online: 4 FEB 2009
  2. Published Print: 27 JUN 2008

ISBN Information

Print ISBN: 9781405157476

Online ISBN: 9781444300857



  • neutropenia;
  • chemotherapy-induced neutropenia;
  • treatment of febrile neutropenia;
  • HIV-associated neutropenia;
  • autoimmune neutropenia;
  • severe autoimmune neutropenia with recurrent fevers and infections;
  • severe chronic neutropenia benefiting from G-CSF administration


This chapter contains sections titled:

  • Introduction

  • Causes of neutropenia

  • Diagnostic tests and strategies

  • Principles of Management

  • Chemotherapy-induced neutropenia

  • Treatment of febrile neutropenia

  • HIV-associated neutropenia

  • Autoimmune Neutropenia

  • Acknowledgments and disclosures

  • References