Chapter 34. Acute Myeloid Leukemia in Adults: Postremission Therapy

  1. Mark A. Crowther MD, MSc, FRCPC Professor Division Director2,3,
  2. Jeff Ginsberg MD, FRCPC Professor4,
  3. Holger J. Schünemann MD, PhD, MSc, FACP, FCCP Professor5,6,
  4. Ralph M. Meyer MD, FRCPC Director Professor7,8 and
  5. Richard Lottenberg MD, FACP Professor9
  1. Cara A. Rosenbaum MD and
  2. Richard A. Larson MD

Published Online: 4 FEB 2009

DOI: 10.1002/9781444300857.ch34

Evidence-Based Hematology

Evidence-Based Hematology

How to Cite

Rosenbaum, C. A. and Larson, R. A. (2008) Acute Myeloid Leukemia in Adults: Postremission Therapy, in Evidence-Based Hematology (eds M. A. Crowther, J. Ginsberg, H. J. Schünemann, R. M. Meyer and R. Lottenberg), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444300857.ch34

Editor Information

  1. 2

    Division of Hematology, McMaster University, Hamilton, Ontario, Canada

  2. 3

    St. Joseph's Hospital, Hamilton, Ontario, Canada

  3. 4

    Department of Medicine, McMaster University, Hamilton, Canada

  4. 5

    CLARITY Research Group, Department of Epidemiology, Italian National Cancer Institute Regina Elena, Rome, Italy

  5. 6

    McMaster University, Hamilton, Canada

  6. 7

    National Cancer Institute of Canada, Clinical Trials Group, Edith Eisenhauer Chair in Clinical Cancer Research, Queen's University, Kingston, Ontario, Canada

  7. 8

    Departments of Oncology and Medicine, Queen's University, Kingston, Ontario, Canada

  8. 9

    Division of Hematology/Oncology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA

Author Information

  1. Section of Hematology/Oncology, Department of Medicine and Cancer Research Center, University of Chicago, Chicago, Illinois, USA

Publication History

  1. Published Online: 4 FEB 2009
  2. Published Print: 27 JUN 2008

ISBN Information

Print ISBN: 9781405157476

Online ISBN: 9781444300857



  • acute myeloid leukemia - postremission;
  • PubMed and MEDLINE database search;
  • intensified chemotherapy in consolidation;
  • acute myeloid leukemia (AML);
  • role of allogeneic HCT in CR1;
  • autologous HCT and chemotherapy - strategy to consolidate first remissions;
  • maintenance chemotherapy role in AML treatment


This chapter contains sections titled:

  • Introduction

  • Literature-search strategy and inclusions

  • What role does intensified chemotherapy play in consolidation?

  • What is the role of allogeneic HCT in CR1?

  • How does autologous HCT compare with chemotherapy as a strategy to consolidate first remissions?

  • Is there a role for maintenance chemotherapy in the treatment of AML?

  • References