Chapter 3. Antimicrobial Resistance Risk Assessment

  1. Luca Guardabassi3,
  2. Lars B. Jensen4 and
  3. Hilde Kruse5
  1. Emma Snary1 and
  2. Scott McEwen2

Published Online: 30 JAN 2009

DOI: 10.1002/9781444302639.ch3

Guide to Antimicrobial Use in Animals

Guide to Antimicrobial Use in Animals

How to Cite

Snary, E. and McEwen, S. (2008) Antimicrobial Resistance Risk Assessment, in Guide to Antimicrobial Use in Animals (eds L. Guardabassi, L. B. Jensen and H. Kruse), Blackwell Publishing, Ltd, Oxford, UK. doi: 10.1002/9781444302639.ch3

Editor Information

  1. 3

    Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Denmark

  2. 4

    National Food Institute, Technical University of Denmark, Copenhagen, Denmark

  3. 5

    Department for Health Surveillance, National Veterinary Institute, Norway

Author Information

  1. 1

    Centre for Epidemiology & Risk Analysis, Veterinary Laboratories Agency – Weybridge, Addlestone, Surrey, UK

  2. 2

    Department of Population Medicine, University of Guelph, Guelph, Ontario, Canada

Publication History

  1. Published Online: 30 JAN 2009
  2. Published Print: 17 APR 2008

ISBN Information

Print ISBN: 9781405150798

Online ISBN: 9781444302639



  • Antimicrobial Resistance Risk Assessment (ARRA);
  • risk analysis and risk assessment frameworks;
  • Codex (3) and World Organisation for Animal Health, OIE (4, 5) Risk Analysis framework comparison;
  • exposure assessment step - most complex in risk assessment;
  • hazard characterisation step - hazard of interest exposure consequence;
  • risk characterisation phase - exposure assessment and hazard characterisation;
  • ARRA and quantitative method;
  • guidance document and OIE risk analysis framework;
  • ARRA role in support of veterinary drug regulatory decision-making in human health risk


This chapter contains sections titled:

  • Introduction

  • Methodological considerations for ARRA

  • Data for ARRA: requirements and sources

  • Examples of ARRA

  • Future perspectives

  • Conclusions

  • References