Chapter 25. Acute Liver Failure

  1. Tony C. K. Tham MD, FRCP, FRCPI Consultant Gastroenterologist Head of School of Medicine3,4,
  2. John S. A. Collins MD Consultant Gastroenterologist5 and
  3. Roy M. Soetikno MD, MS Chief Associate Professor6,7
  1. Aijaz Ahmed MD1 and
  2. Emmet B. Keeffe MD Professor of Medicine2

Published Online: 9 FEB 2009

DOI: 10.1002/9781444303292.ch25

Gastrointestinal Emergencies, Second Edition

Gastrointestinal Emergencies, Second Edition

How to Cite

Ahmed, A. and Keeffe, E. B. (2008) Acute Liver Failure, in Gastrointestinal Emergencies, Second Edition (eds T. C. K. Tham, J. S. A. Collins and R. M. Soetikno), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303292.ch25

Editor Information

  1. 3

    The Ulster Hospital, Dundonald, Belfast, Northern Ireland, UK

  2. 4

    Northern Ireland deanery, UK

  3. 5

    Royal Victoria Hospital, Belfast, Northern Ireland, UK

  4. 6

    GI Section, VA Palo Alto Health Care System, USA

  5. 7

    Stanford University, USA

Author Information

  1. 1

    Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA, USA

  2. 2

    Stanford University School of Medicine, Stanford, CA, USA

Publication History

  1. Published Online: 9 FEB 2009
  2. Published Print: 28 NOV 2008

ISBN Information

Print ISBN: 9781405146340

Online ISBN: 9781444303292



  • acute liver failure;
  • viral hepatitis;
  • drug-induced liver injury;
  • metabolic conditions associated with acute liver failure;
  • management of complications;
  • acute liver failure complications - malaise or nausea;
  • hepatic encephalopathy and cerebral edema;
  • hypoglycemia in setting of fulminant hepatic failure;
  • coagulopathy


This chapter contains sections titled:

  • Introduction

  • Definition

  • Epidemiology

  • Etiology

  • Clinical manifestations

  • Management of complications

  • Treatment

  • Prognosis

  • References