Chapter 2. Laboratory Assessment of Platelet Function and the Effects of Antiplatelet Agents

  1. Stephen D. Wiviott MD Assistant Professor Investigator
  1. Alan D. Michelson MD Director Professor of Pediatrics and
  2. A. L. Frelinger III PhD Associate Director Associate Professor of Pediatrics

Published Online: 19 FEB 2009

DOI: 10.1002/9781444303339.ch2

Antiplatelet Therapy In Ischemic Heart Disease

Antiplatelet Therapy In Ischemic Heart Disease

How to Cite

Michelson, A. D. and Frelinger, A. L. (2008) Laboratory Assessment of Platelet Function and the Effects of Antiplatelet Agents, in Antiplatelet Therapy In Ischemic Heart Disease (ed S. D. Wiviott), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303339.ch2

Editor Information

  1. Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, TIMI Study Group, Boston, MA, USA

Author Information

  1. Center for Platelet Function Studies, University of Massachusetts Medical School, Worcester, MA USA

Publication History

  1. Published Online: 19 FEB 2009
  2. Published Print: 28 NOV 2008

Book Series:

  1. The AHA Clinical Series

Book Series Editors:

  1. Elliott Antman MD, FAHA

Series Editor Information

  1. Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, TIMI Study Group, Boston, MA, USA

ISBN Information

Print ISBN: 9781405176262

Online ISBN: 9781444303339

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Keywords:

  • platelet function tests;
  • bleeding time - first test of platelet function;
  • laboratory assessment of platelet function;
  • platelet function tests for monitoring of response to aspirin;
  • platelet aggregometry;
  • thromboelastograph (TEG) updated as TEG® Platelet Mapping™ system;
  • analysis of leukocyte–platelet aggregates;
  • VASP phosphorylation state

Summary

This chapter contains sections titled:

  • Introduction

  • The bleeding time

  • Platelet aggregometry

  • VerifyNow®

  • TEG® PlateletMapping System™

  • Impact® cone and plate(let) analyzer

  • PFA-100®

  • Whole blood flow cytometry

  • Summary

  • References