Chapter 68. Steroid-Resistant Nephrotic Syndrome

  1. Donald A. Molony MD3,4 and
  2. Jonathan C. Craig MD, PhD5,6
  1. Annabelle Chua MD1 and
  2. Peter Yorgin MD2

Published Online: 4 MAR 2009

DOI: 10.1002/9781444303391.ch68

Evidence-Based Nephrology

Evidence-Based Nephrology

How to Cite

Chua, A. and Yorgin, P. (2008) Steroid-Resistant Nephrotic Syndrome, in Evidence-Based Nephrology (eds D. A. Molony and J. C. Craig), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303391.ch68

Editor Information

  1. 3

    Division of Renal Disease and Hypertension, University of Texas, USA

  2. 4

    Houston Medical School, Houston, Texas, USA

  3. 5

    School of Public Health, University of Sydney, Australia

  4. 6

    Department of Nephrology, The Children's Hospital at Westmead, Sydney, Australia

Author Information

  1. 1

    Section of Pediatric Nephrology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA

  2. 2

    Section of Pediatric Nephrology, Loma Linda University Children's Hospital, Loma Linda, California, USA

Publication History

  1. Published Online: 4 MAR 2009
  2. Published Print: 5 DEC 2008

ISBN Information

Print ISBN: 9781405139755

Online ISBN: 9781444303391

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Keywords:

  • steroid-resistant nephrotic syndrome (SRNS);
  • treatment of SRNS - methods;
  • calcineurin inhibitor therapy;
  • corticosteroid therapy - oral corticosteroid therapy;
  • purine synthesis inhibitors;
  • antineoplastic and immunosuppressant medications;
  • use of combination therapy;
  • intravenous CPA;
  • nonimmunosuppressant therapy;
  • pheresis-based therapies

Summary

This chapter contains sections titled:

  • Introduction

  • Treatment of SRNS: methods

  • Calcineurin inhibitor therapy

  • Corticosteroid therapy

  • Purine synthesis inhibitors

  • Alkylating agents

  • Other antineoplastic and immunosuppressant medications

  • Combination therapy

  • Nonimmunosuppressant therapy

  • Pheresis-based therapies

  • Antibody therapy

  • Bone marrow transplantation

  • Conclusions

  • References