Chapter 9. Acute Tubular Necrosis

  1. Donald A. Molony MD2,3 and
  2. Jonathan C. Craig MD, PhD4,5
  1. Jay L. Koyner MD and
  2. Patrick T. Murray MD

Published Online: 4 MAR 2009

DOI: 10.1002/9781444303391.ch9

Evidence-Based Nephrology

Evidence-Based Nephrology

How to Cite

Koyner, J. L. and Murray, P. T. (2008) Acute Tubular Necrosis, in Evidence-Based Nephrology (eds D. A. Molony and J. C. Craig), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303391.ch9

Editor Information

  1. 2

    Division of Renal Disease and Hypertension, University of Texas, USA

  2. 3

    Houston Medical School, Houston, Texas, USA

  3. 4

    School of Public Health, University of Sydney, Australia

  4. 5

    Department of Nephrology, The Children's Hospital at Westmead, Sydney, Australia

Author Information

  1. Section of Nephrology, University of Chicago, Chicago, Illinois, USA

Publication History

  1. Published Online: 4 MAR 2009
  2. Published Print: 5 DEC 2008

ISBN Information

Print ISBN: 9781405139755

Online ISBN: 9781444303391



  • acute kidney injury (AKI);
  • acute tubular necrosis;
  • prevention of ATN from amphotericin B;
  • prevention of ATN from amphotericin B - lipid-based formulations;
  • prevention of ATN from rhabdomyolysis;
  • loop diuretics;
  • pharmacologic therapy of established ATN;
  • therapy of established ATN with fenoldopam


This chapter contains sections titled:

  • Introduction

  • Diagnosis

  • Pathophysiology

  • Outcomes

  • Preventive strategies

  • Pharmacologic therapy of established ATN

  • Summary

  • References