Chapter 38. The Kinetics of Intracellular Calcium and Arrhythmogenesis in Ischemia/Reperfusion: A Calcium-Centric Mechanism of Arrhythmia

  1. Mohammad Shenasa MD, FACC, FAHA, FESC, FHRS Attending Physician2,
  2. Gerhard Hindricks MD, PhD Head3,
  3. Martin Borggrefe MD4 and
  4. Günter Breithardt MD, FESC, FACC, FHRS Professor of Medicine (Cardiology) Head5
  1. Nabil El-Sherif MD,
  2. Gil Bub PhD and
  3. Vikram Lakireddy MD

Published Online: 26 FEB 2009

DOI: 10.1002/9781444303438.ch38

Cardiac Mapping, Third Edition

Cardiac Mapping, Third Edition

How to Cite

El-Sherif, N., Bub, G. and Lakireddy, V. (2008) The Kinetics of Intracellular Calcium and Arrhythmogenesis in Ischemia/Reperfusion: A Calcium-Centric Mechanism of Arrhythmia, in Cardiac Mapping, Third Edition (eds M. Shenasa, G. Hindricks, M. Borggrefe and G. Breithardt), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303438.ch38

Editor Information

  1. 2

    Department of Cardiovascular Services, O'Connor Hospital, San Jose, California, USA

  2. 3

    Department of Electrophysiology, University Leipzig, Heart Center, Leipzig, Germany

  3. 4

    Department of Medicine-Cardiology, University Hospital of Mannheim, Mannheim, Germany

  4. 5

    Department of Cardiology and Angiology, Hospital of the Westfälische Wilhelms, University of Münster, Münster, Germany

Author Information

  1. State University of New York, Downstate Medical Center, New York Harbor VA Healthcare System, Brooklyn, NY, USA

Publication History

  1. Published Online: 26 FEB 2009
  2. Published Print: 5 DEC 2008

ISBN Information

Print ISBN: 9781405175722

Online ISBN: 9781444303438

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Keywords:

  • intracellular calcium in ischemia/reperfusion;
  • ischemia/reperfusion - elevated intracellular calcium and alteration in calcium kinetics;
  • contrasting effects of ischemia on kinetics of Cai transient (CaiT);
  • spatial heterogeneity of APD and electrical alternans;
  • repolarization maps;
  • dynamics of intracellular CaiT/Vm uncoupling and arrhythmogenesis;
  • dominant frequency (DF);
  • towards quantification of asynchrony in VT

Summary

This chapter contains sections titled:

  • Introduction

  • Technical Considerations

  • References