Chapter 5. Clinical Trials and Response to CRT

  1. Kenneth A. Ellenbogen MD2 and
  2. Angelo Auricchio MD, PhD Director3
  1. Kenneth M. Stein MD Associate Professor of Medicine

Published Online: 26 FEB 2009

DOI: 10.1002/9781444303452.ch5

Pacing to Support the Failing Heart

Pacing to Support the Failing Heart

How to Cite

Stein, K. M. (2008) Clinical Trials and Response to CRT, in Pacing to Support the Failing Heart (eds K. A. Ellenbogen and A. Auricchio), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444303452.ch5

Editor Information

  1. 2

    Kontos Professor of Cardiology, Medical College of Virginia, Richmond, VA, USA

  2. 3

    Heart Failure Service, Fondazione Cardiocentro Ticino, Lugano, Switzerland

Author Information

  1. Maurice and Corinne Greenberg Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, New York, NY, USA

Publication History

  1. Published Online: 26 FEB 2009
  2. Published Print: 5 DEC 2008

Book Series:

  1. The AHA Clinical Series

Book Series Editors:

  1. Elliott Antman

Series Editor Information

  1. Samuel A. Levine Cardiac Unit, Brigham and Women's Hospital, USA

ISBN Information

Print ISBN: 9781405175340

Online ISBN: 9781444303452



  • clinical trials and CRT;
  • clinical response to cardiac resynchronization;
  • resynchronization and survival;
  • unresolved questions and ongoing trials;
  • atrial fibrillation;
  • CRT reducing congestive heart failure symptoms;
  • precise lead placement affecting response to therapy - controversial


This chapter contains sections titled:

  • Key Points

  • Introduction

  • Clinical response to cardiac resynchronization

  • Resynchronization and survival

  • Unresolved questions and ongoing trials

  • Summary

  • References